56342-58-6Relevant academic research and scientific papers
A novel biomimetic synthesis of (S)-(-)-zearalenone: Via macrocyclization and transannular aromatization
Miyatake-Ondozabal, Hideki,Barrett, Anthony G.M.
, p. 6331 - 6334 (2010)
On heating, a hydroxy-keto-dioxinone underwent retro-Diels-Alder fragmentation and the resultant α,γ-diketo-ketene was efficiently trapped intramolecularly by a secondary alcohol to provide a macrocyclic triketo-lactone. Following ketal hydrolysis, transannular aromatization gave the resorcylate natural product, (S)-(-)-zearalenone.
