56355-41-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-4,5-dimethyl-thiazole is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-4,5-dimethyl-thiazole serves as an intermediate for the production of agrochemicals, including pesticides and herbicides. Its incorporation aids in the creation of effective solutions for crop protection and management.
Used in Dye Industry:
2-Chloro-4,5-dimethyl-thiazole is employed as an intermediate in the production of dyes, contributing to the development of a wide range of colorants used in various industries, such as textiles, plastics, and printing inks.
Used in Fragrance Industry:
This chemical compound is also used as a building block in the synthesis of fragrances, adding to the complexity and variety of scents used in perfumes, cosmetics, and other scented products.
Used in Flavor Industry:
2-Chloro-4,5-dimethyl-thiazole contributes to the creation of diverse flavors in the food and beverage industry, enhancing taste profiles and providing unique sensory experiences for consumers.
Check Digit Verification of cas no
The CAS Registry Mumber 56355-41-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,5 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56355-41:
(7*5)+(6*6)+(5*3)+(4*5)+(3*5)+(2*4)+(1*1)=130
130 % 10 = 0
So 56355-41-0 is a valid CAS Registry Number.
56355-41-0Relevant academic research and scientific papers
New Methods for the Introduction of Substituents into Thiazoles
Begtrup, Mikael,Hansen, Lars Bo L.
, p. 372 - 383 (2007/10/02)
New methods for the regioselective introduction of substituents into thiazoles have been developed using thiazole, 2-phenylthiazole and 4,5-dimethylthiazole as representative thiazoles.Improved halogenation methods, displacement of hydroxy groups in combination with dehalogenation at C-5 yield all eight possible 2-phenyl-4-halo-, 5-halo and 4,5-dihalo-thiazoles in which halogen is chlorine and bromine.Peracid oxidation of the thiazoles gives the corresponding thiazole 3-oxides.These are not activated towards halogenation but are deprotonated with sodium hydride.The anion formed react with electrophiles such as paraformaldehyde, 2,2-dimethylpropanal, 2,2-dimethylpropanoyl chloride, hexachloroethane, tetrabromomethane, and dimethyl disulfide leading to the introduction of carbon substituents, halogen, and methylthio groups.In these reactions, the reactivity of the thiazole ring positions decreases in the order 2 than 5 than 4.Monoselectivity is low when halogen and methylthio groups are introduced since these substituents enhance the acidity of adjacent ring protons. 2-Phenyl-4,5-dihalothiazole 3-oxides lose the 5-halogen when treated with sulfite ion.Trimethyloxonium tetrafluoroborate O-methylates thiazole 3-oxides.Thiazole N-oxides also react with acetyl chloride and phosphorus oxychloride to afford chlorothiazoles in a non-selective manner.Phosphorus trichloride deoxygenates thiazole 3-oxides.
