56374-49-3Relevant academic research and scientific papers
Alkylpotassium-Catalyzed Benzylic C-H Alkylation of Alkylarenes with Alkenes
Sato, Io,Yamashita, Yasuhiro,Kobayashi, Shū
, p. 240 - 250 (2019/01/04)
Catalytic benzylic C-H alkylation reactions of alkylarenes with alkenes such as β-substituted styrenes and vinylsilanes have been achieved by utilizing alkylpotassium as a catalyst. Various substituted toluene derivatives can be alkylated under mild reaction conditions to afford the desired functionalized hydrocarbons in moderate to high yields.
Catalytic Direct-Type Addition Reactions of Alkylarenes with Imines and Alkenes
Yamashita, Yasuhiro,Suzuki, Hirotsugu,Sato, Io,Hirata, Tsubasa,Kobayashi, Shū
supporting information, p. 6896 - 6900 (2018/05/14)
Catalytic addition reactions of very weakly acidic nonactivated alkylarenes such as toluene and its derivatives were developed by using a strongly basic mixed catalyst system under mild reaction conditions. The addition reactions with imines and alkenes proceeded smoothly under proton-transfer conditions to afford the desired products in good to high yields, and high levels of regio- and stereoselectivity were achieved. It was also revealed that the asymmetric addition reaction of an alkylarene was possible.
Reaction of 1,2-Diphenylethane with D2
Guthrie, Robert D.,Shi, Buchang,Rajagopal, Venkatsubramanian,Ramakrishnan, Sreekumar,Davis, Burtron H.
, p. 7426 - 7432 (2007/10/02)
The reaction of 1,2-diphenylethane (DPE) with D2 (2000 psi) was studied at 450 deg C.The results of GC/MS and NMR analysis of reaction products and of products from reactions of 1,2-diphenylethane-1,1-d2, 1,2-di(phenyl-d5)ethane, and 1,2,3,4-tetraphenylbutane confirm a mechanistic scheme in which the main process for introduction of D is the reaction of 1,2-diphenylethyl radical with D2.This reaction, though energetically uphill, competes with termination processes because of the high concentration of D2 relative to that of radical species.The reaction generates D atoms which attack aromatic ring positions to give substitution for both H and alkyl substituents.Evidence is provided for D and H atom transfer between aliphatic positions in DPE in the presence of either N2 or H2 and between aromatic positions only when provoked by H2 or D2.Only a small amount of exchange between aromatic and aliphatic positions is observed under any conditions.The attack of D atoms at H-carrying aromatic positions makes H atoms available for transfer to other aromatic positions.The process results in a D2-provoked generation of benzene-d0.Mechanistic alternatives for these and other processes are discussed.
Electrocatalytic Reduction of Benzal Chloride by Cobalt(I)(salen). A Mechanistic Investigation
Fry, Albert J.,Sirisoma, U. Nilantha
, p. 4919 - 4924 (2007/10/02)
Benzal chloride (6) is converted to a mixture consisting primarily of cis- and trans-stilbene (12) by the action of electrochemically-generated cobalt(I)(salen)(1-) (5).The process involves a saquence involving electrocatalytic conversion of benzal chloride to a mixture of the stereoisomeric 1,2-dichloro-1,2-diphenylethanes (10), followed by electrocatalyzed conversion of the latter to 12.Voltammograms of Co(II)(salen) (4) in the presence of varying amounts of 6 exhibit peaks both before and after that due to reduction of 4.The voltammetric data and other chemical evidence is interpreted in light of previously-suggested mechanism for stilbene formation.
Conversion of benzal chloride to stilbene by electrogenerated cobalt(I) (salen) a doubly electrocatalytic process
Fry, Albert J.,Sirisoma, U. Nilantha,Lee, Agnes S.
, p. 809 - 812 (2007/10/02)
Benzal chloride is converted to a mixture consisting primarily of cis- and trans-stilbene by the action of electrochemically-generated cobalt(I)(salen). The process involves a sequence involving electrocatalytic conversion of benzal chloride to a mixture of meso- and dl -1,2-dichloro-1,2-diphenylethane, followed by electrocatalyzed conversion of the latter to the stilbenes. Each of the diastereomeric dichlorides affords the same mixture of stilbenes under the reaction conditions.
Mannich/Friedel-Crafts Preparations of 1-(Arylmethyl)benzotriazoles and Synthetic Transformations of their Lithio Derivatives
Katritzky, Alan R.,Gordeev, Mikhail F.,Greenhill, John V.,Steel, Peter J.
, p. 1111 - 1118 (2007/10/02)
The synthesis of 1-(arylmethyl)benzotriazoles by Mannich type reactions of benzene, toluene, p-xylene and chlorobenzene with 1-chloromethylbenzotriazole in the presence of aluminium halides is reported.Alkylation of their lithio derivatives followed by th
THE GAS-PHASE REDUCTIVE DIMERIZATION OF BENZALDEHYDE ON A FUSED IRON CATALYST
Glebov, L. S.,Shuikin, A. N.,Kliger, G. A.,Mikaya, A. I.,Zaikin, V. G.,et al.
, p. 814 - 817 (2007/10/02)
The gas-phase heterogeneous catalytic reductive dimerization of benzaldehyde to trans-stilbene and dibenzyl was carried out on a reduced promoted fused iron catalyst.The mechanism of this reaction was examined.
The reaction of benzotrihalides and benzal halides with magnesium. Synthetic and mechanistic studies
Ashby, E. C.,Al-Fekri, Dheya M.
, p. 275 - 292 (2007/10/02)
The benzotrihalides (PhCX3) where X = Cl, Br, and F were allowed to react with magnesium in THF at room temperature.When the halide was chloride or bromide, the trihalide gave diphenylacetylene in high yield in addition to several minor products which were identified.No reaction was observed when the halide was fluoride.When the corresponding dichloride was allowed to react with magnesium in THF, stilbene was formed as the major product.The possible mechanisms for these reactions are discussed.
REACTION OF SULFUR WITH ORGANIC COMPOUNDS XXVI. REACTIONS OF SULUR WITH TOLUENE AND ITS EXO-SUBSTITUTED DERIVATIVES
Przewocki, K.,Voronkov, M. G.,Przewocka, L.,Varnke, Z.
, p. 2147 - 2154 (2007/10/02)
The reactions of sulfur with toluene and its exo-substituted derivatives of the PhCH2X type, where X = H, Cl, Br, I, OH, OCOMe, COOH, CH2Ph, SH, C(OH)(Ph)CH2Ph, and PhCH=Y, where Y = O, CHPh, C(Ph)CH2Ph, and also with 2-phenylbenzothiophene at 200 deg C and at the autogenous pressure were studied.In all cases the products of these reactions were bibenzyl, E- and Z-stilbenes, 2-phenylbenzothiophene, E- and Z-1,2,3-triphenylpropenes, 1,2,3-triphenylpropane, 2-phenyl-3-benzylbenzothiophene, tetraphenylthiophene, and pentaphenylcyclopentadiene, the ratios of whichare determined by the nature of the substituent X or Y.The high-molecular-weight reaction products with M 240 (34 compounds) were identified.
