56379-87-4

Basic information

• Product Name: Carbamic acid, 1-naphthalenyl-, phenyl ester
• CAS NO: 56379-87-4
• Molecular Formula: C17H13NO2
• Molecular Weight: 263.296
• Mol File: 56379-87-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, 1-naphthalenyl-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, 1-naphthalenyl-, phenyl ester(56379-87-4)
• EPA Substance Registry System: Carbamic acid, 1-naphthalenyl-, phenyl ester(56379-87-4)

Safety Data

• Hazardous Substances Data: 56379-87-4(Hazardous Substances Data)

Upstream product

• 86-84-0 1-Naphthyl isocyanate 
• 108-95-2 phenol 
• 102-09-0 bis(phenyl) carbonate 
• 134-32-7 1-amino-naphthalene 
• 917-61-3 sodium isocyanate 
• 90-13-1 1-Chloronaphthalene 

Relevant articles and documents

Benzothiazole derivatives and their uses

The present invention relates to benzothiazole derivatives and their uses, specifically to compounds shown in formula I or stereoisomers thereof and pharmaceutically acceptable salts, solvates or prodrugs thereof, methods of preparation thereof, and pharmaceutical compositions containing the compounds, wherein the substituentsR1,R2,R8 , X, Y, Z, Q have the meaning given in the instruction manual. The present invention further relates to the application of compounds of formula I in the preparation of drugs for the treatment and / or prevention of sEH-mediated diseases, in particular in the preparation of drugs for the treatment of inflammatory diseases, cardiovascular and cerebrovascular diseases, diabetes mellitus, diabetic complications, diabetes-related diseases, fibrotic diseases, neurological and psychiatric diseases, pain, ulcerative diseases and the like.

Biomimetic building-up of the carbamic moiety: The intermediacy of carboxyphosphate analogues in the synthesis of N-aryl carbamate esters from arylamines and organic carbonates promoted by phosphorus acids

The reaction of aromatic amines with dimethyl carbonate (DMC) or diphenyl carbonate (DPC) in the presence of organo-phosphorus acids [Ph2P(O)OH (1); (PhO)2P(O)OH (2); (BuO)2P(O)OH/(BuO)P(O)(OH)2 equimolar mixture (3)] affords carbamate esters, ArNHC(O)OR (R = Me, Ph) with high selectivity. The catalytic role played by the P-acid has been investigated and rationalized in terms of a reaction mechanism involving the intermediate formation of a carbonic-phosphinic(phosphoric) anhydride X2P(O)OC(O)OR (X = Ph, PhO; R = Me, Ph). The proposed mechanism shows intriguing analogies with the mechanism of formation of carbamate anion in living systems by carbamoyl phosphate synthetase (CPS) enzyme. Copyright