56410-68-5Relevant articles and documents
NOVEL 6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
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Paragraph 1000, (2014/12/09)
The invention provides novel compounds having the general formula: wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as or pharmaceutically acceptable salts, or tautomerism isomers, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.
Synthesis of 6-Phosphonoalkyl Tetrahydro-4-pyrimidinecarboxylic Acids as NMDA Receptor Antagonists
Bigge, Christopher F.,Wu, Jiang-Ping,Drummond, James R.
, p. 7659 - 7662 (2007/10/02)
The title compounds were prepared via a sequence which involved as the key steps a Michael reaction between nitroalkyl phosphonates and protected dehydroalanine and subsequent cyclization of the α,γ-diamino esters.Key Words: 6-phosphonoalkyl tetrahydro-4-