56431-75-5Relevant academic research and scientific papers
An efficient synthesis of cyclopropyl silyl ketones
Honda, Mitsunori,Nakae, Kenta,Nishizawa, Toshiaki,Suda, Mitsuhiro,Kunimoto, Ko-Ki,Segi, Masahito
scheme or table, p. 9500 - 9508 (2012/01/02)
The reaction of silylcyclopropyl bromides with dichloromethyl methyl ether in the presence of n-butyllithium is investigated. Under basic reaction conditions, the corresponding cyclopropylidene derivatives are exclusively obtained. The resulting cyclopropylidene compounds are subjected to protonolysis or trapping with electrophiles in a one-pot to give the cyclopropyl silyl ketone derivatives in good yields. Acidic treatment of derived cyclopropyl silyl ketone allows isomerization to give the thermodynamically favorable trans form exclusively.
Acid-catalyzed reaction behavior of 1-silylcyclopropylmethanols
Honda, Mitsunori,Mita, Takahito,Nishizawa, Toshiaki,Sano, Toru,Segi, Masahito,Nakajima, Tadashi
, p. 5751 - 5754 (2007/10/03)
Treatment of 1-silylcyclopropylmethanols with TsOH in methanol gives different homoallyl ethers depending upon the configuration of substituents on cyclopropane ring and the kinds of substituents on carbinyl carbon. Especially, the reaction of cyclopropyl
SYNTHESIS AND REACTIONS OF 1-BROMOCYCLOPROPYLTRIMETHYLSILANE DERIVATIVES
Hiyama, Tamejiro,Kanakura, Akihiro,Morizawa, Yoshitomi,Nozaki, Hitosi
, p. 1279 - 1280 (2007/10/02)
The title compounds derived from 1,1-dibromocyclopropanes are transformed into (1) cyclopropyltrimethylsilanes via 1-trimethylsilylcyclopropyllithium species, (2) 1-alkylidenecyclopropanes by the Peterson-olefination, and (3) 1-acetyl(or 1-allyl)cyclopropylsilanes with dibutylcopperlithium and acetyl chloride (or allyl bromide).
