564441-87-8Relevant academic research and scientific papers
1,3-bis(diarylmethylidene)-2-methylidenecyclohexanes in cycloaddition and cyclodimerization reactions. The role of stereoelectronic factors
Klimova, Elena I.,Garcia, Marcos Martinez,Klimova, Tatiana,Ortega, S. Hernandez,Bakinovsky, Leon V.
, p. 1210 - 1215 (2003)
Cycloaddition and cyclodimerization reactions of 1,3-dibenzylidene- and 1,3-bis(p-methoxybenzylidene)-2-methyl-idenecyclohexanes, i.e., the diaryltrienes with fixed S-cis-configurations of exocyclic double bonds are studied. These compounds undergo in situ cyclodimerization of the [4+2]-type upon dehydration of the precursor tertiary alcohols and form endo-adducts in the Diels-Alder reaction with N-phenylmaleimide. In the presence of CF3COOH, acid-catalyzed cyclodimerization takes place leading to methylidene-substituted spirocylodimers, which undergo intramolecular cyclization upon prolonged contact with CF3COOH to form a fused carbocyclic system containing a central, 'three-petal' fragment of six-membered rings.
