564476-31-9

Upstream product

• 994-30-9 triethylsilyl chloride 
• 2785-98-0 2,5-dimethoxybenzoic acid 
• 564476-26-2 C₄₉H₈₂O₁₂Si₃ 
• 564476-29-5 7-(triethylsilyl)-2-debenzoyl-2-(2,5-dimethoxybenzoyl)-baccatin III 
• 564476-28-4 C₃₇H₅₄O₁₂Si 
• 564476-27-3 2-debenzoyl-2-(2,5-dimethoxybenzoyl)-10-deacetylbaccatin 
• 204580-30-3 10-O-deacetyl-2-O-debenzoyl-7,10,13-O-tris(triethylsilyl)baccatin III 
• 564476-30-8 C₆₀H₉₅NO₁₇Si₂ 

Relevant academic research and scientific papers

Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies

The targeted delivery of taxoids, in the form of taxane-antibody immunoconjugates, requires the preparation of taxoids containing moieties suitable for their conjugation to monoclonal antibodies. A series of taxoids incorporating a disulfide-containing li

Cytotoxic agents containing novel potent taxanes and their therapeutic use

Included within the scope of the present invention are potent taxanes containing a linking group. Also included is a cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for inducing cell death in select

Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use

A cytotoxic agent comprising one or more polyethylene glycol-containing taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more polyethylene glycol-containing taxanes covalently bonded to a cell binding agent through a linking group, and (B) a pharmaceutically acceptable carrier, diluent or excipient. A method for killing selected cell populations comprising contacting target cells or tissue containing target cells with an effective amount of a cytotoxic agent comprising one or more polyethylene glycol-containing taxanes linked to a cell binding agent.