56456-19-0

Usage

Uses

Used in Pharmaceutical Industry:
2-Benzyloxyethyl chloroformate is used as a reagent for the synthesis of various pharmaceutical compounds. Its ability to form carbamates allows it to be employed in the production of drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Benzyloxyethyl chloroformate is used as a versatile reagent for the formation of carbamates and other related compounds. Its reactivity makes it a valuable tool in the development of new chemical entities with potential applications in various industries.
Used in Research and Development:
2-Benzyloxyethyl chloroformate is also utilized in research and development settings, where it can be employed to study the properties and reactions of carbamates. This can lead to the discovery of new compounds and applications in various fields, including pharmaceuticals, materials science, and environmental science.

InChI:InChI=1/C10H11ClO3/c11-10(12)14-7-6-13-8-9-4-2-1-3-5-9/h1-5H,6-8H2

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 622-08-2 2-Benzyloxyethanol 
• 75-44-5 phosgene 

Downstream Products

• 869189-75-3 1-[2-(benzyloxy)ethyl] 4-methyl 4-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]methylpiperidine-1,4-dicarboxylate 
• 62124-67-8 1-(2-benzyloxyethoxycarbonyl)-2-(4-thiazolyl)-benzimidazole 
• 56456-26-9 3-Acetylamino-5-[(2-benzyloxy-ethoxycarbonylamino)-methyl]-2,4,6-triiodo-benzoic acid 
• 1228443-13-7 C₄₈H₃₆N₂O₁₀ 
• 162538-01-4 Dimethyl-carbamic acid 2-benzyloxy-ethyl ester 
• 56456-25-8 3-Amino-5-[(2-benzyloxy-ethoxycarbonylamino)-methyl]-2,4,6-triiodo-benzoic acid 

Relevant academic research and scientific papers

5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, an optionally substituted lower alkenyl group, a cycloalkyl group or a lower acyl group etc.; Q is a hydrogen atom or an optionally substituted lower alkyl group; and Z is a hydrogen atom or a hydroxy group etc., or a pharmaceutically acceptable salt thereof, which exert a potent and selective activated blood coagulation factor X inhibitory activity and is useful as an agent for the prevention or treatment of a disease occurred associating an activated blood coagulation factor X, a pharmaceutical composition comprising the same and an intermediate thereof. These compounds are useful as preventives or remedies for various diseases such as brain infarction, cerebral thrombosis, cerebral embolism, TIA, cerebral vascular jerk, Alzheimer's diseases, myocardial infarction, heart attack, heart failure, thrombosis, pulmonary infarction and pulmonary embolism.

Aminodiol HIV protease inhibitors. Synthesis and structure - Activity relationships of P1/P1′ compounds: Correlation between lipophilicity and cytotoxicity

A series of novel aminodiol inhibitors of HIV protease based on the lead compound 1 with structural modifications at P1′ were synthesized in order to reduce the cytotoxicity of 1. We have observed a high degree of correlation between the lipophilicity and the cytotoxicity of this series of inhibitors. It was found that appropriate substitution at the para position of the P1′ phenyl group of 1 resulted in the identification of equipotent (both against the enzyme and in cell culture) compounds (101, 10m, 10n, and 15c) which possess significantly decreased cytotoxicity.

Antifungal 1-substituted benzimidazoles

New benzimidazoles substituted at the 1-position with carbonyl substituents and at the 2-position with a 4-thiazolyl group are effective fungicides and anthelmintics exhibiting particularly useful hydrophilic and lypophilic effects. The compounds as well as processes for their preparation are described along with antifungal and anthelmintic compositions for their use. The 1-position substituent is a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy carbonyl group of a chain with up to 4 ethoxy groups connected to the carbonyl. The compounds are generally prepared by contacting a 1-unsubstituted benzimidazole with a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy chloroformate.