56473-15-5

Basic information

• Product Name: Hydrazinecarbothioamide, N,N'-1,6-hexanediylbis-
• Synonyms: Hydrazinecarbothioamide,N,N'-1,6-hexanediylbis;4,4'-hexanediyl-bis thiosemicarbazide;hexane-1,6-dithiosemicarbazide;4,4'-Hexandiyl-bis-thiosemicarbazid
• CAS NO: 56473-15-5
• Molecular Formula: C8H20N6S2
• Molecular Weight: 264.41500
• Mol File: 56473-15-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 145 °C
• Boiling Point: 433.0±55.0 °C(Predicted)
• Density: 1.240±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Hydrazinecarbothioamide, N,N'-1,6-hexanediylbis-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarbothioamide, N,N'-1,6-hexanediylbis-(56473-15-5)
• EPA Substance Registry System: Hydrazinecarbothioamide, N,N'-1,6-hexanediylbis-(56473-15-5)

Safety Data

• Hazardous Substances Data: 56473-15-5(Hazardous Substances Data)

Upstream product

• 45131-67-7 N,N'-(hexamethylene)bisdithiocarbamic acid 
• 871-67-0 disodium hexamethylenetetrathiocarbamate 
• 7803-57-8 hydrazine hydrate 
• 75-15-0 carbon disulfide 
• 124-09-4 1,6-Hexanediamine 
• 21494-66-6 3-[6-(4-oxo-2-thioxothiazolidin-3-yl)hexyl]-2-thioxothiazolidin-4-one 
• 5586-70-9 hexamethylene 1,6-diisothiocyanate 
• 13208-75-8 N,N'-hexamethylenebis(2-thioxo-1,3-thiazin-2-one) 
• 822-06-0 Hexamethylene diisocyanate 

Downstream Products

• 56473-32-6 C₂₄H₂₈N₆O₄S₂ 
• 56473-25-7 C₂₂H₂₆Cl₂N₆S₂ 
• 56473-61-1 C₂₄H₃₄N₈S₄ 
• 56473-30-4 C₂₂H₂₆N₈O₄S₂ 
• 56602-52-9 C₂₆H₃₄N₈O₂S₂ 
• 56473-36-0 1,1'-Dibenzoyl-4,4'-hexamethylen-bis(thiosemicarbazid) 
• 56473-62-2 C₂₂H₃₀N₈S₄ 
• 56473-31-5 C₂₄H₂₈N₆O₄S₂ 
• 56513-55-4 C₂₂H₄₂N₈S₄ 
• 56513-56-5 N,N'-bis-[5-(2-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-hexane-1,6-diamine 
• 56473-41-7 1,1'-Di(m-nitro-benzoyl)-4,4'-hexamethylen-bis(thiosemicarbazid) 
• 56473-38-2 1,1'-Di(p-brom-benzoyl)-4,4'-hexamethylen-bis(thiosemicarbazid) 
• 56473-23-5 C₂₂H₂₆Br₂N₆S₂ 
• 56473-42-8 1,1'-Di(p-nitro-benzoyl)-4,4'-hexamethylen-bis(thiosemicarbazid) 

Relevant articles and documents

Synthesis and biological evaluation of 2-benzoylpyridine thiosemicarbazones in a dimeric system: Structure-activity relationship studies on their anti-proliferative and iron chelation efficacy

Thiosemicarbazone chelators represent an exciting class of biologically active compounds that show great potential as anti-tumor agents. Our previous studies demonstrated the potent anti-tumor activity of the 2'-benzoylpyridine thiosemicarbazone series. W

Synthesis and characterization of new thiazolidin-4-one derivatives

The synthesis of some new functionalized thiazolidin-4-one derivatives has been described. The N-substituted-thiosemicarbazides 3a-3i were obtained though the reaction of alkylamines 2a-2i, carbon disulfide, and hydrazine hydrate. The condensation reaction between 3a-3i and 4-amino-2-methanesulfanylpyrimidine-5- carboxaldehyde 1 afforded the thiosemicarbazones 4a-4i. The corresponding thiazolidin-4-ones 5a-5i were prepared by cyclization of 4a-4i with ethyl bromoacetate. The structures of the final products were confirmed by IR, 1H NMR, 13C NMR, and HRMS.

Synthesis of new antimicrobials. V. Synthesis of alkylenebis(thiosemicarbazides) and their related compounds

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