56485-04-2

Usage

Uses

Used in Flavoring Industry:
2-oxo-3-phenyl-propanal is used as a flavoring agent for its distinctive sweet, floral scent, enhancing the taste and aroma of various food products.
Used in Pharmaceutical Synthesis:
2-oxo-3-phenyl-propanal is utilized as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Health and Wellness Applications:
Due to its antioxidant and anti-inflammatory properties, 2-oxo-3-phenyl-propanal is studied for potential health benefits, which may include supporting the body's natural defenses against oxidative stress and inflammation.

InChI:InChI=1/C9H8O2/c10-7-9(11)6-8-4-2-1-3-5-8/h1-5,7H,6H2

Upstream product

• 186581-53-3 diazomethane 
• 1638-63-7 2-acetoxy-2-phenylacetyl chloride 
• 7149-58-8 diethoxyacetic acid piperidinyl amide 
• 6921-34-2 benzylmagnesium chloride 
• 104-53-0 3-phenyl-propionaldehyde 
• 4250-02-6 1-diazo-3-phenyl-2-propanone 
• 17173-38-5 1-acetoxy-3-diazo-1-phenyl-acetone 
• 20461-78-3 3-Diazo-1-methoxy-carbonyloxy-1-phenyl-aceton 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 77252-94-9 3-phenyl methylglyoxal dimethyl acetal 

Downstream Products

• 93-58-3 benzoic acid methyl ester 
• 100-52-7 benzaldehyde 
• 611-73-4 Benzoylformic acid 
• 65-85-0 benzoic acid 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 4358-87-6 (RS)-methyl mandelate 
• 50909-86-9 2,8-dibenzyl-6-(4-hydroxyphenyl)imidazo[1,20-a]pyrazin-3(7H)one 
• 19256-31-6 1,1-diethoxy-3-phenylpropane-2-one 
• 186495-21-6 9-Methoxymethyl-1-phenylacetyl-9H-β-carboline-3-carboxylic acid ethyl ester 
• 186495-29-4 6-Bromo-9-methoxymethyl-1-phenylacetyl-9H-β-carboline-3-carboxylic acid ethyl ester 
• 70217-82-2 2-benzyl-8-benzyl-6-(phenyl)imidazo[1,2-a]pyrazin-3(7H)-one 

Relevant academic research and scientific papers

Luminescence-based methods and probes for measuring cytochrome P450 activity

The present invention provides methods, compositions, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferin or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. Upon addition of the luciferin derivative or other luminogenic molecule into a P450 reaction, the P450 enzyme metabolizes the molecule into a bioluminescent enzyme substrate, e.g., luciferin and/or luciferin derivative metabolite, in a P450 reaction. The resulting metabolite(s) serves as a substrate of the bioluminescent enzyme, e.g., luciferase, in a second light-generating reaction. Luminescent cytochrome P450 assays with low background signals and high sensitivity are disclosed and isoform selectivity is demonstrated. The present invention also provides an improved method for performing luciferase reactions which employs added pyrophosphatase to remove inorganic pyrophosphate, a luciferase inhibitor which may be present in the reaction mixture as a contaminant or may be generated during the reaction. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors.

Oxidation of diazo compounds by triphenyl phosphite ozonide. Quenching of singlet oxygen by diazo compounds

The reaction of triphenyl phosphite ozonide with various types of diazo compounds results in their oxidation, which is accomplished by singlet oxygen (1O2) evolved during thermal decomposition of the ozonide.A decrease in the ionization potential of the substrate results in an increase in the overall rate constant of quenching of 1O2.In the case of 9-diazofluorene, the main channel of 1O2 quenching is physical quenching. - Key words: phosphite ozonides, singlet oxygen; diazo compounds; ionization potential; rate constant of quenching of singlet oxygen.

Selenium-Mediated Conversion of Alkynes into α-Dicarbonyl Compounds

The reaction of terminal and internal alkynes with diphenyl diselenide and ammonium peroxydisulfate in methanol proceeds smoothly to give α-keto acetals and α-keto ketals, respectively.This one-pot procedure is suggested to proceed through the initial formation of phenylselenenyl sulfate, a strong electrophilic reagent which effects the methoxyselenenylation of the alkynes.The addition products thus formed suffer methoxydeselenenylation giving the observed products and regenerating the phenylselenenylating agent.In some cases the reaction can be carried out using only catalytic amounts of diphenyl diselenide.The same reaction carried out in the presence of water or of ethylene glycol gives the unprotected or the diprotected α-dicarbonyl compounds, respectively.