565-62-8Relevant articles and documents
Cassis and Green Tea: Spontaneous Release of Natural Aroma Compounds from β-Alkylthioalkanones
B?ttig, Sarah,Bochet, Christian G.,Egger, Timothy,Flachsmann, Felix,Gey, Olga
, (2021/10/19)
In depth headspace analysis of the slow degradation of β-alkylthioalkanones in ambient air led to the discovery of a novel δ-cleavage pathway, by which β-mercaptoketones are released. Since β-mercaptoketones are potent natural aroma compounds occurring in many fruits, herbs and flowers, the discovery of an enzyme-independent molecular precursor for this class of high-impact molecules is of practical importance. Moreover, the formation of β-diketones and aldehydes by concomitant oxidation at the α-sulfur-position enhances the versatility of this class of aroma precursors. A mechanistic model is proposed which suggests that the oxidative degradation occurs through a novel Pummerer-type rearrangement of initially formed persulfoxides.
Facile Synthesis of Onychines
Arita, Mao,Yokoyama, Soichi,Asahara, Haruyasu,Nishiwaki, Nagatoshi
, p. 2007 - 2013 (2019/04/26)
The FeCl 3 -mediated condensation of an α-phenylenamino ester and an enone proceeds efficiently to afford a 2-phenylnicotinate. The subsequent intramolecular Friedel-Crafts reaction yielded an onychine framework. Modifications at the 2-, 3-, and 8-positions of the onychine framework were easily achieved by altering the enamino esters and enones, which facilitated the discovery of potentially bioactive compounds.
Method for continuously producing 3-methyl-3-pentene-2-one by reactive distillation
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Paragraph 0024; 0025; 0026; 0027; 0028-0035, (2019/07/10)
The invention discloses a method for continuously producing 3-methyl-3-pentene-2-one by reactive distillation. 2-butanone and acetaldehyde are used as raw materials, a novel microspherical polymer ionic liquid P(VB-VS)HSO4 is adopted as a catalyst, acetaldehyde and 2-butanone are subjected to an aldol condensation reaction in a reactive distillation column to generate 3-methyl-3-pentene-2-one, andthen, a reaction solution is delivered into a reduced-pressure distillation column and is subjected to reactant and product separation to obtain high-purity 3-methyl-3-pentene-2-one. According to themethod, the novel microspherical polymer ionic liquid is used as a reaction catalyst instead of traditional strong acid/alkali, so that the reaction condition is mild, the conversion rate and selectivity of acetaldehyde are high, side reactions are reduced, meanwhile, an acid-base neutralization process in a traditional process is further omitted, the energy loss and wastewater treatment are greatly reduced, and the method is capable of saving energy and environment-friendly; and the superfluous 2-butanone can be further used as a reaction raw material after being separated, so that the resource loss is reduced.
