565-65-1

Upstream product

• 3869-56-5 1,3-dibromo-1,1,2-trifluoro-butane 
• 401-52-5 4-iodo-1,1,2-trifluorobut-1-ene 
• 374-26-5 3,4-Dichlor-3,4,4-trifluor-buten-(1) 
• 374-25-4 4-bromo-3-chloro-3,4,4-trifluorobutene-1 
• 10493-44-4 1,1,2-trifluoro-4-bromobut-1-ene 
• 18599-22-9 4-bromo-3,3,4,4-tetrafluorobut-1-ene 
• 100-52-7 benzaldehyde 
• 116-14-3 polytetrafluoroethylene 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 3932-66-9 2,3,3-trifluoro-1-cyclobutene 
• 92818-42-3 1,2,2,5,6,6-hexafluorotricyclo<3.3.0.0^6,8>octane 
• 113894-32-9 3-chloro-4-(phenylthio)-1,1,2-trifluoro-1-butene 
• 113894-43-2 (Z)-1,2-difluoro-1-phenyl-1,3-butadiene 
• 113894-38-5 (E)-1,2-difluoro-1-phenyl-1,3-butadiene 

Relevant academic research and scientific papers

Preparation of trifluorovinyl compounds by lithium salt-promoted monoalkylation of tetrafluoroethene

Treatment of tetrafluoroethene (TFE) with diethylzinc in the presence of lithium iodide gave 1,1,2-trifluoro-1-butene in moderate yield. In the absence of lithium iodide, however, the nucleophilic addition of diethylzinc to TFE proceeded very slowly to afford ethyl 1,1,2,2-tetrafluorobutylzinc. The addition of lithium iodide to a solution of ethyl-1,1,2,2-tetrafluorobutylzinc resulted in a smooth transformation into 1,1,2-trifluoro-1-butene. In the presence of lithium chloride, the reaction of TFE with benzyl or allyl Grignard reagents afforded the corresponding monosubstituted products in good to excellent yields.

Novel introduction of a tetrafluoroethylene (-CF2CF 2-) unit into organic molecules

The reductive coupling of 4-bromo-3,3,4,4-tetrafluorobut-1-ene with 2.4 equivalents of various carbonyl compounds proceeded very smoothly in the presence of 2.4 equivalents of MeLi/LiBr-free at -78°C for two hours, giving the corresponding adducts in high

Fluorinated butene derivatives and methods for their preparation

New chemical reactions of 1,1,2-trifluoro-1,3-butadiene provide simple access to a series of new fluorinated alkene derivatives. These derivatives provide a simple, general methodology for the stereocontrolled preparation of 2-fluoro-2-alkenoate esters an

1,1,2-Trifluoro-1,3-butadiene: A Convenient C4 Intermediate for Functionalized Monofluoroolefins

The regioselective methoxybromination of 1,1,2-trifluoro-1,3-butadiene to give (Z)-4-bromo-1-methoxy-1,1,2-trifluoro-2-butene (3a) is reported.This can easily be transformed into a wide range of (Z)-2-fluoro-2-alkenoates (4a-c, 5).The reaction of benzenes