Xi:Irritant;565-67-3Relevant academic research and scientific papers
OPEN-FLASK HYDROBORATION AND THE USE THEREOF
-
Paragraph 0046; 0049; 0059; 0060; 0061, (2018/03/25)
The present disclosure generally relates to a process for hydroboration of an alkene or alkyne using ammonia borane (AB). In particular, the present invention relates to hydroboration of an alkene or alkyne in the presence of air or moisture, and a clean process for facile preparation of an alcohol by oxidizing the organoborane so formed with hydrogen peroxide. The products, including aminodialkylboranes, ammonia trialkylborane complexes, as well as various alcohols so prepared, are within the scope of this disclosure.
Iridium Clusters Encapsulated in Carbon Nanospheres as Nanocatalysts for Methylation of (Bio)Alcohols
Liu, Qiang,Xu, Guoqiang,Wang, Zhendong,Liu, Xiaoran,Wang, Xicheng,Dong, Linlin,Mu, Xindong,Liu, Huizhou
, p. 4748 - 4755 (2017/12/15)
C?H methylation is an attractive chemical transformation for C?C bonds construction in organic chemistry, yet efficient methylation of readily available (bio)alcohols in water using methanol as sustainable C1 feedstock is limited. Herein, iridium nanocatalysts encapsulated in yolk–shell-structured mesoporous carbon nanospheres (Ir@YSMCNs) were synthesized for this transformation. Monodispersed Ir clusters (ca. 1.0 nm) were encapsulated in situ and spatially isolated within YSMCNs by a silica-assisted sol–gel emulsion strategy. A selection of (bio)alcohols (19 examples) was selectively methylated in aqueous phase with good-to-high yields over the developed Ir@YSMCNs. The improved catalytic efficiencies in terms of activity and selectivity together with the good stability and recyclability were contributable to the ultrasmall Ir clusters with oxidation chemical state as a consequence of the confinement effect of YSMCNs with interconnected nanostructures.
A non-dissociative open-flask hydroboration with ammonia borane: Ready synthesis of ammonia-trialkylboranes and aminodialkylboranes
Ramachandran, P. Veeraraghavan,Drolet, Michael P.,Kulkarni, Ameya S.
, p. 11897 - 11900 (2016/10/09)
Under open-flask conditions, ammonia borane hydroborates olefins in refluxing tetrahydrofuran. Unlike conventional hydroboration, the Lewis base (ammonia) is not dissociated from the boron center. Terminal alkenes selectively provide ammonia-trialkylborane complexes. On the other hand, internal alkenes afford aminodialkylboranes via a metal-free hydroboration-dehydrogenation sequence. Alkaline hydrogen peroxide oxidation of the products provides the corresponding alcohols in high yields.
Enantioselective Ethylation of Various Aldehydes Catalyzed by Readily Accessible Chiral Diols
G?k, Ya?ar,Kili?arslan, Seda,G?k, Halil Zeki,Karayi?it, ?lker ümit
, p. 593 - 598 (2016/08/27)
Four chiral C2-symmetric diols were synthesized in a straightforward three-step reaction and demonstrated excellent enantioselectivities and good overall yields. Their catalytic activities were examined via the addition of diethylzinc to various aldehydes. The enantioselective addition of diethylzinc to 2-methoxybenzaldehyde gave the corresponding chiral secondary alcohol with high yields (up to 95%) and moderate to good enantiomeric excess (up to 88%). All synthesized ligands were evaluated in the addition of diethylzinc to various aldehydes in the presence of an additional metal such as Ti(IV) complexes. Chirality 28:593–598, 2016.
Facile Protocol for Catalytic Frustrated Lewis Pair Hydrogenation and Reductive Deoxygenation of Ketones and Aldehydes
Mahdi, Tayseer,Stephan, Douglas W.
supporting information, p. 8511 - 8514 (2015/11/27)
A series of ketones and aldehydes are reduced in toluene under H2 in the presence of 5 mol % B(C6F5)3 and either cyclodextrin or molecular sieves affording a facile metal-free protocol for reduction to alcohols. Similar treatment of aryl ketones resulted in metal-free deoxygenation yielding aromatic hydrocarbons.
Enabling catalytic ketone hydrogenation by frustrated lewis pairs
Mahdi, Tayseer,Stephan, Douglas W.
supporting information, p. 15809 - 15812 (2015/02/19)
Hydrogenation of alkyl and aryl ketones using H2 is catalytically achieved in 18 examples using 5 mol % B(C6F5)3 in an ethereal solvent. In these cases the borane and ether behave as a frustrated Lewis pair to activate H2 and effect the reduction.
Organoleptic compound
-
Page/Page column 7; 8, (2014/08/06)
The present invention is directed to a novel compound, but-2-enoic acid 1,2-dimethyl-butyl ester, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of but-2-enoic acid 1,2-dimethyl-butyl ester.
Novel Organoleptic Compound
-
Paragraph 0025; 0026, (2014/09/03)
The present invention is directed to a novel compound, but-2-enoic acid 1-ethyl-2-methyl-propyl ester, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of but-2-enoic acid 1-ethyl-2-methyl-propyl ester.
Organoleptic compound
-
Page/Page column 5, (2014/07/21)
The present invention is directed to a novel compound, but-2-enoic acid 1-ethyl-2-methyl-propyl ester, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of but-2-enoic acid 1-ethyl-2-methyl-propyl ester.
SYNTHESIS OF HIGH CALORIC FUELS AND CHEMICALS
-
Paragraph 00109, (2013/05/23)
In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.
