56539-58-3Relevant academic research and scientific papers
Concise Construction of the Tricyclic Core of Bullataketals Enabled by a Biomimetic Intermolecular (3 + 3) Type Cycloaddition
Tan, Haibo,Liu, Hongxin,Chen, Xinzheng,Yuan, Yunfei,Chen, Kai,Qiu, Shengxiang
, p. 4050 - 4053 (2015)
A remarkable TFA-mediated method for the construction of a biologically interesting tricyclic ketal skeleton was uncovered by starting from a variety of readily available acylphloroglucinol and diacylphloroglucinol substrates. This approach, which mimics a biosynthetic olefin isomerization/hemiacetalization/dehydration/(3 + 3) type cycloaddition sequence through a 2H-furan-1-ium intermediate, establishes a viable synthetic strategy for efficient synthesis of bullataketals' analogs.
Atom-Transfer Radical Addition of Alcohols to Aliphatic Alkynes
Liu, Zhong-Quan,Xiao, Yingxia
, p. 9577 - 9583 (2019/08/26)
An intermolecular hydrogen bond-promoted atom-transfer radical addition of simple alcohols to aliphatic alkynes is demonstrated here. Through this strategy, a variety of allyl alcohols can be synthesized in high selectivity and yields. Furthermore, this work reveals the relationship between selectivity and the substrate. ?
