5655-26-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(chroman-4-yl)acetic acid is used as a potential therapeutic agent for the treatment of autoimmune disorders and inflammatory diseases. Its anti-inflammatory and immunomodulatory effects make it a promising candidate for the development of new drugs to manage these conditions.
Used in Drug Development:
2-(chroman-4-yl)acetic acid is used as a compound of interest in drug development due to its unique structure and potential physiological effects. Its pharmacological properties may contribute to the discovery of new drugs with improved efficacy and safety profiles.
Used in Medicinal Chemistry:
2-(chroman-4-yl)acetic acid is used as a starting material or a building block in the synthesis of new compounds with potential therapeutic applications. Its unique structure and pharmacological properties make it a valuable tool for medicinal chemists in the design and optimization of novel drug candidates.

Upstream product

• 119304-96-0 ethyl 2-(3,4-dihydro-2H-1-benzopyran-4-yl)-ethanoate 
• 121278-28-2 ethyl (E)-2-(2,3-dihydro-4H-1-benzopyran-4-ylidene)acetate 
• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 124-38-9 carbon dioxide 
• 87280-00-0 1‐bromo‐2‐(but-3‐en‐1‐yloxy)benzene 
• 121278-46-4 N-(2-hydroxy-1-phenylethyl)-(3,4-dihydro-1(2H)-benzopyran-4-yl)ethanamide 

Downstream Products

• 119304-88-0 N-phenethyl-2-(chroman-4-yl)-1-methylethylamine 
• 119304-98-2 (chroman-4-yl)acetone 

Relevant academic research and scientific papers

Facile synthesis of 2,3-dihydrobenzofuran-3-ylacetic acids by novel electrochemical sequential aryl radical cyclization-carboxylation of 2-allyloxybromobenzenes using methyl 4-tert-butylbenzoate as an electron-transfer mediator

Facile synthesis of 2,3-dihydrobenzofuran-3-ylacetic acids and related analogues was successfully carried out by a novel electrochemical aryl radical generation and its 5-exo cyclization followed by a carboxylation sequence of 2-allyloxybromobenzenes by u

Benzopyran derivatives and pharmaceutical compositions containing them

New benzopyran derivatives of formula: STR1 in which R1 is hydrogen, halogen, hydroxy, alkoxy, nitro, amino, alkylsulphonamido, bis(alkylsulphonyl) amino or acylamino, X is nitrogen or a >CH-radical R is a radical of formula: STR2 in which A de

An Efficient Procedure for the Preparation of a Class of α-Carboxy-γ-Lactones, and Studies on their Transformation to α-Methylene Derivatives.

Attempted preparation of the bromohydrins (5a-b) gave interesting results.Ring opening of epoxides (1) and bromohydrins (5), the precursors of (1), with diethyl malonate anion under refluxing benzene has been shown to be the method of choice for the preparation of lactonic esters (acids)(3) in excellent yields.Methylenation of the lactonic acids provided the α-methylene-γ-lactones (4a-d).A possible pathway for the synthesis of the cis-lactones (22a-c) has also been investigated briefly.