56577-39-0Relevant articles and documents
A simple method for N-acylation of adenosine and cytidine nucleosides using carboxylic acids activated in-situ with carbonyldiimidazole
Sinha,Sinha, Nanda D.,Davis,Davis, Peter,Schultze,Schultze, Lisa M.,Upadhya,Upadhya, Krishna
, p. 9277 - 9280 (2007/10/02)
Carboxylic acids are activated with 1,1'-carbonyldiimidazole in acetonitrile to form N-acylimidazoles which are then treated with per-trimethylsilyl ethers of nucleosides adenosine or cytidine at ambient temperature to generate exclusively N-acylated-Aden
Improvements in Oligodeoxyribonucleotide Synthesis using Phenoxyacetyl as Amino Protecting Group
Singh, Ramendra K.,Misra, K.
, p. 409 - 417 (2007/10/02)
Phenoxyacetyl group has been used successfully for the protection of exocyclic amino function on purine and pyrimidine bases of 2'-deoxynucleosides.In the case of 2'-deoxycytidine, quantitative selective protection has been achieved under controlled condi