56586-44-8

Upstream product

• 98-88-4 benzoyl chloride 
• 764-22-7 (2S,3R)-2-amino-1,3-octadecanediol 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 3102-56-5 dihydrosphingosine 
• 112-67-4 n-hexadecanoyl chloride 
• 14531-34-1 methyl 3-oxooctadecanoate 
• 103512-55-6 (4S)-3-benzoyl-4r-hydroxymethyl-5c-pentadecyl-2ξ-phenyl-oxazolidine 
• 2304-76-9 (+/-)-erythro-2-benzoylamino-1,3-bis-benzoyloxy-octadecane 
• 102874-89-5 (2S,3R)-2-benzylideneamino-octadec-4t-ene-1,3-diol 
• 103044-89-9 (2S,3R)-2-benzylideneamino-octadecane-1,3-diol 
• 103512-35-2 (4S)-3-benzoyl-4r-hydroxymethyl-5c-pentadec-1-en-t-yl-2ξ-phenyl-oxazolidine 
• 100-52-7 benzaldehyde 

Downstream Products

• 2304-76-9 erythro-(2S,3S)-N,O,O-tribenzoyl-dihydrosphingosine 

Relevant academic research and scientific papers

The synthesis and biological characterization of a ceramide library

A facile synthesis of a combinatorial ceramide library and their activities in the NF-κB pathway and in apoptosis induction/prevention were demonstrated. A novel NF-κB activating molecule was discovered among ceramide containing β-galactose, and the structural requirements of ceramides for apoptosis induction was elucidated. Copyright

Stereoselective synthesis of sphinganine by means of modified asymmetric borane reduction

Efficient stereoselective synthesis of sphinganine by the asymmetric borane reduction of α-oxoketoxime trityl ethers is described. Both threo and erythro sphinganine could be obtained with high enantioselectivities by using borane-N,N-diethylaniline complex as a reducing agent.