56635-61-1Relevant academic research and scientific papers
ORTHO METALATION DIRECTED BY α-AMINO ALKOXIDES. AN IMPROVED SYNTHESIS OF ORTHO-SUBSTITUTED ARYL KETONES
Comins, Daniel L.,Brown, Jack D.
, p. 5465 - 5468 (2007/10/02)
Ortho-substituted aryl ketones are prepared from N--N-methylbenzamides via ortho lithiation of intermediate α-amino alkoxides, formed in situ by addition of RLi.An ortho lithiation of N--N-methylbenzamide is also described.
Long-range anisotropic effects of long chain amides
Budzikiewicz, Herbert,Vieth, Peter-Eric,Krueger, Uwe
, p. 825 - 840 (2007/10/02)
In 1H-NMR spectra of amids with long-chain aliphatic N-substituents one observes - despite of the free mobility of the aliphatic chain - splitting of the signals of the terminal methyl groups which is caused by the hindered rotation of the amide bond. - Keywords: Amides; Hindered rotation; 1H-NMR
