5664-29-9Relevant articles and documents
Design, synthesis, and biological activities of novel 2-alkylpyrrole derivatives
Li, Yongqiang,Wang, Ziwen,Zhang, Pengxiang,Liu, Yuxiu,Xiong, Lixia,Wang, Qingmin
, p. 1410 - 1414 (2015/04/27)
To investigate the alkyl analog of insecticide chlorfenapyr, two series of 2-alkyl-4-bromo-5-(trifluoromethyl)pyrrole-3-carbonitriles were synthesized with a cycloaddition as the key step. The target products were characterized by 1H-NMR spectroscopy, elemental analysis, or HRMS. The insecticidal, herbicidal, and antifungal activities of the target compounds were evaluated and found that these compounds did not show much insecticidal activity, but compounds 4, 10, and 11 had very good fungicidal activities against Alternaria solani and Fusarium oxysporum. Moreover, compound 4 had an outstanding inhibition effect against pigweed.
Synthesis of α-amino acids by addition of putative azido radicals to α-methoxy acrylonitriles derived from aldehydes and ketones
Clive, Derrick L. J.,Etkin, Nola
, p. 2459 - 2462 (2007/10/02)
α-Methoxy acrylonitriles, available from aldehydes and ketones, react with sodium azide in the presence of ceric ammonium nitrate to give azido nitrates; from these compounds, α-amino acids are obtained by sequential treatment with sodium acetate in acetic acid and then methanolic potassium carbonate, followed by hydrogenation.
The Synthesis of Amino Acids via Organoboranes
O'Donnell, Martin J.,Falmagne, Jean-Bernard
, p. 1168 - 1169 (2007/10/02)
The reaction of the acetate (1) with organoboranes provides a convenient, new route to amino acids.
