56653-47-5Relevant academic research and scientific papers
Alternate method for the synthesis of N-alkyl/aralkyl-2-(α-hydroxy alkyl/aralkyl)benzimidazoles via regiospecific acetylation
Dubey,Reddy, P.V.V. Prasada,Srinivas
, p. 1675 - 1681 (2008/02/01)
Acetylation of 1H-2-(α-hydroxyalkyl/aryl)benzimidazoles 2 with Ac2O results in the regiospecific formation of O-acetoxy derivative 3, which on alkylation with alkylating agents in nonaqueous media under phase-transfer catalytic conditions affords N-alkyl
Investigations of unsaturated azoles. 13. Synthesis and some reactions of 1-alkylbenzimidazoles
Popov
, p. 672 - 681 (2007/10/03)
Methods of direct alkylation of benzimidazoles by haloalkanes in homogeneous medium and under phase transfer catalysis conditions together with cyanoethylation by acrylonitrile are reported. The dealkylation of quaternary benzimidazole salts was also studied. 1997 Plenum Publishing Corporation.
