56676-83-6

Upstream product

• 86771-37-1 5,8-Dimethoxy-3-(2-methyl-[1,3]dithiolan-2-yl)-3,4-dihydro-2H-naphthalen-1-one 
• 89533-75-5 3-methylene-4-oxopentanoic acid 
• 150-78-7 1,4-dimethoxybezene 
• 123-76-2 levulinic acid 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 60732-17-4 2,5-dimethoxybenzyl bromide 
• 33654-63-6 3-acetyl-4-(2', 5'-dimethoxyphenyl)-2-butanone 
• 24599-58-4 2,5-dimethoxy toluene 
• 33654-64-7 ethyl-3,3-diacetyl-4-(2', 5',-dimethoxyphenyl)-butanoate 
• 86771-34-8 methyl-3-acetyl-4-(2', 5'-dimethoxyphenyl)-butanoate 
• 86771-35-9 4-(2,5-Dimethoxy-phenyl)-3-(2-methyl-[1,3]dithiolan-2-yl)-butyric acid methyl ester 
• 86771-36-0 4-(2,5-Dimethoxy-phenyl)-3-(2-methyl-[1,3]dithiolan-2-yl)-butyric acid 
• 75759-59-0 3-acetyl-4-(2', 5'-dimethoxyphenyl)-butanoic acid 

Downstream Products

• 67122-26-3 (+/-)4-demethoxy-7,9-dideoxydaunomycinone 
• 80027-54-9 2-acetyl-6-(2-carboxy-6-methoxybenzyl)-1,2,3,4-tetrahydro-8-methoxy-5-naphthol 

Relevant academic research and scientific papers

Synthesis and biological activity of novel shikonin analogues

A series of shikonin analogues with side chain variants have been synthesized and evaluated for antitumor activity. These novel analogues show a broad spectrum of in vitro cytotoxicity against various cancer cell lines. Additionally, some analogues were a

Facile total syntheses of idarubicinone-7-β-D-glucuronide: Convenient preparations of AB-ring synthon using some carboxylic acid derivatives

Regiospecific syntheses of idarubicinone coupled with D-glucuronic acid are described. Cyclization of dimethoxybenzene with carboxylic acid derivatives in polyphosphoric acid (PPA) in one step afforded the naphthalenones 7, which were transformed to the (

A new and simple approach for the synthesis of 3-acetyl-3,4-dihydro-1(2H)-naphthalenones and 3,4-dihydro-3-(2-methyl-1,3-dithiolan-2-yl)-1(2H)-naphthalenones

3-Acetyl-3,4-dihydro-1(2H)-naphthalenones and 3,4-dihydro-3-(2-methyl-1,3-dithiolan-2-yl)-1(2H)-naphthalenones are prepared using levulinic acid as starting substrate.

1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics

Compounds represented by the formula (I) STR1 wherein R is hydrogen or hydroxyl, one of X and Y is fluorine and the other is hydrogen or both X and Y are fluorine, and Su is a hydrogen atom or a sugar moiety; where Su is a sugar moiety, the compounds are useful anticancer antibiotics; pharmaceutical preparations containing the antibiotics and a method for inhibiting the growth of mammalian tumors are also disclosed.

A CONVENIENT APPROACH TO THE TOTAL SYNTHESIS OF (+/-) 4-DEMETHOXYDAUNOMYCINONE

A convenient and most practical approach to the synthesis of (+/-) 4-demethoxydaunomycinone starting from 2-methylhydroquinone is described.