56692-48-9

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 13509-91-6 (2,3,4,5,6-pentafluorobenzyl)triphenylphosphonium bromide 
• 1765-40-8 (bromomethyl)pentafluorobenzene 
• 768-56-9 4-Phenylbut-1-ene 
• 363-72-4 Pentafluorobenzene 
• 1616842-30-8 (E)-1,2,3,4,5-pentafluoro-6-(4-phenylbut-2-en-1-yl)benzene 
• 3360-41-6 4-phenyl-butan-1-ol 
• 392-56-3 Hexafluorobenzene 
• 64283-87-0 4-phenyl-1-iodobutane 
• 56693-03-9 1,2,3,4,5-pentafluoro-6-[(1E,3E)-4-phenyl-1,3-butadien-1-yl]benzene 

Downstream Products

• 56692-49-0 1,2,4,5-Tetrafluoro-3-(4-phenyl-butyl)-benzene 
• 56692-52-5 1-(4'-Bromomethyl-2',3',5',6'-tetrafluorophenyl)-4-phenylbutan 
• 56692-51-4 [2,3,5,6-Tetrafluoro-4-(4-phenyl-butyl)-phenyl]-methanol 
• 56692-50-3 2,3,5,6-Tetrafluoro-4-(4-phenyl-butyl)-benzaldehyde 
• 56693-04-0 1-Bromomethyl-4-[4-(4-bromomethyl-phenyl)-butyl]-2,3,5,6-tetrafluoro-benzene 

Relevant academic research and scientific papers

Photoredox Polyfluoroarylation of Alkyl Halides via Halogen Atom Transfer

Polyfluoroarene moieties are of interest in medicinal chemistry, agrochemicals, and material sciences. Herein, we present the first polyfluoroarylation of unactivated alkyl halides via a halogen atom transfer process. This method converts primary, secondary, and tertiary alkyl halides into the respective polyfluoroaryl compounds in good yields in the presence of amide, carbamate, ester, aromatic, and sulfonamide moieties, including derivatives of complex bioactive molecules. Mechanistic work revealed that this transformation proceeds through an alkyl radical generated after the halogen atom transfer.

Palladium-catalyzed aerobic oxidative allylic C-H arylation of alkenes with polyfluorobenzenes

An aerobic oxidative cross-coupling reaction of alkenes with polyfluorobenzenes, through palladium-catalyzed allylic C-H activation, is reported. This attractive route provides a new way to forge allylic C-C bonds of valuable products, in good yields, with high regioselectivity.