56715-75-4Relevant academic research and scientific papers
Synthesis and biological evaluation of novel 3-aryl-4-methoxy N-alkyl maleimides
Gosavi, Kirankumar S.,Mahale, Keshao A.,Patil, Nilesh S.,Patil, Sambhaji V.
, p. 473 - 478 (2021/09/28)
In the present investigation, a series of 3-aryl-4-methoxy N-alkyl maleimide 5a-l have been synthesized and screened for their antimicrobial activity against one Gram positive bacteria (S. aureus), one Gram negative bacteria (E. coli) and fungal strains (C. albicans, C. tropicalis, A. Niger and A. clavatus). The structures of the compounds have been substantiated by their IR, NMR, mass and elemental analysis. The minimum inhibitory concentrations (MICs) of synthesized maleimides have been determined by broth microdilution method. Of the newly synthesized maleimides, compounds 5c, 5f, 5h, 5i, 5k and 5l registered significant activity against the tested microorganisms.
Regioselectivity control in metal hydride reductions of substituted maleic anhydrides
Kayser, Margaret M.,Breau, Livain,Eliev, Sonia,Morand, Peter,Ip, H. S.
, p. 104 - 109 (2007/10/02)
A systematic study of reductions of unsymmetrically substituted maleic anhydrides by a variety of metal hydride reagents indicates that the high regioselectivity observed in these reactions is controlled chiefly by electronic factors.
