6362-63-6

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL-3-CYANO-3-PHENYLPYRUVATE 97 is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block in the development of new drugs and medications.
Used in Chemical Synthesis:
ETHYL-3-CYANO-3-PHENYLPYRUVATE 97 is used as a reagent in the preparation of various chemical compounds, such as 2-(3,4-Dimethoxyphenyl)-5-phenyl-3,4-dioxoadiponitrile. Its cyano and phenyl groups make it a valuable component in the synthesis of complex organic molecules.

InChI:InChI=1/C12H11NO3/c1-2-16-12(15)11(14)10(8-13)9-6-4-3-5-7-9/h3-7,10H,2H2,1H3

Upstream product

• 140-29-4 phenylacetonitrile 
• 95-92-1 oxalic acid diethyl ester 
• 127919-46-4 t-butyl [2-(5-amino-4-phenyl-3-isoxazolecarboxamido)ethyl]carbamate 
• 26388-11-4 Natrium-phenylacetonitril 
• 56024-17-0 (2,4-dioxo-3-phenyl-oxazolidin-5-ylidene)-phenyl-acetonitrile 
• 141-52-6 sodium ethanolate 
• 64-17-5 ethanol 
• 397887-10-4 3-cyano-2-oxo-3-phenyl-propionic acid methyl ester 

Downstream Products

• 56715-75-4 3-cyano-2-methoxy-3-phenyl-acrylic acid ethyl ester 
• 6362-93-2 4,5-diphenyl-dihydro-furan-2,3-dione 
• 858031-46-6 2-oxo-3-phenyl-2H-benzo[h]chromene-4-carboxylic acid ethyl ester 
• 3333-14-0 2,3-diphenylpropionitrile 
• 56715-99-2 3-cyano-2-oxo-3-phenyl-butyric acid ethyl ester 
• 853928-41-3 7,8-dihydroxy-2-oxo-3-phenyl-2H-chromene-4-carboxylic acid ethyl ester 
• 6362-65-8 4-phenyl-pyrrolidine-2,3-dione 
• 6476-18-2 4-phenyl-pyrrolidine-2,3,5-trione 
• 6362-70-5 5-benzyl-4-phenyl-dihydro-furan-2,3-dione 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 6362-56-7 ethyl 3-phenylpyruvate 
• 41339-39-3 4-Oxo-3-phenyl-1-oxa-5-aza-spiro[5.5]undec-2-ene-2-carboxylic acid ethyl ester 
• 52923-48-5 3-hydroxy-2-phenylpropanenitrile 
• 56715-75-4 ethyl(3-cyano-2-methoxy)cinnamate 

Relevant academic research and scientific papers

Maleic anhydride derivatives used as conjugation agents of anti-tumor agents on desired carriers

The present invention relates to anti-tumor-conjugation agent-protein compounds of the general formula I: STR1 wherein, R1 and R2 are each independently selected from hydrogen atom, C1-4 alkyl, C1-4 alkoxy, C1-6 carboxyalkyl, phenyl, or phenyl substituted by at least one of hydroxy, halogen, lower alkyl, lower alkoxy, or nitro, with the proviso that R1 and R2 cannot be simultaneously a hydrogen, and when one of R1 or R2 is a hydrogen, the other one cannot be --CH2 COOH; A is the residue of an anti-tumor agent containing at least one amino group available to form an amide bound; and B is a free ε-lysine containing residue selected from a peptide or a protein.

COMPOUNDS FOR TREATING AND PREVENTING COGNITIVE DISEASES AND DEPRESSION AND METHODS OF MAKING SAME

Ethylenediamine monoamides of the formula R--CO--NH--CH2 --CH2 --NH2. wherein R is one of groups in which R1 is phenyl monohalophenyl, monolower-alkylphenyl, monolower-alkoxypheynl, monotrifluoromethylphenyl, monocyanophenyl or monoaryl-lower-alkoxyphenyl, dihalophenyl, furyl, thienyl or monohalothienyl, R2 is hydrogen, halogen or amino, R3, R5 and R7 each are phenyl, monohalophenyl, dihalophenyl, thienyl, furyl or monohalofuryl, R4 and R6 each are hydrogen or amino and R8 is hydrogen or lower-alkyl, as well as their pharmaceutically usable acid addition salts are disclosed. The compounds have monoamine oxidase inhibiting properties with low toxicity and are useful for the treatment of depressive states and cognitive disorders

Regioselectivity control in metal hydride reductions of substituted maleic anhydrides

A systematic study of reductions of unsymmetrically substituted maleic anhydrides by a variety of metal hydride reagents indicates that the high regioselectivity observed in these reactions is controlled chiefly by electronic factors.

Tetramic acid analogs of pulvinic acid

Tetramic acid analogs of pulvinic acid having anti-arthritic activity are prepared by treatment of the corresponding tetramic acid lactones with an alkali metal lower alkoxide.

Ester derivatives of pulvinic acid

Pharmaceutical compositions having anti-arthritic activity comprising an ester derivative of pulvinic acid and methods of producing anti-arthritic activity by administering internally said compositions. Certain of the pulvinic acid derivatives are novel compounds per se.

Anti-arthritic compositions comprising N-heterocyclic pulvinic acid amides and methods of producing anti-arthritic activity

N-Heterocyclic pulvinic acid amides having antiarthritic activity are prepared by treating the corresponding pulvinic acid with a heterocyclic amine.