56719-08-5

Usage

Uses

Used in Organic Synthesis:
3-(2,5-dichlorophenyl)-3-oxopropanenitrile is utilized as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows for versatile reactions, making it a valuable component in the synthesis of a wide range of organic molecules.
Used in Pesticide and Herbicide Formulations:
In the agricultural industry, 3-(2,5-dichlorophenyl)-3-oxopropanenitrile is employed as an active ingredient in the formulation of pesticides and herbicides. Its pesticidal and herbicidal properties contribute to the control of pests and weeds, thereby enhancing crop protection and yield.
Used in Pharmaceutical Production:
3-(2,5-dichlorophenyl)-3-oxopropanenitrile is used as a building block in the pharmaceutical industry for the development of new drugs. Its chemical structure provides a foundation for the synthesis of various medicinal compounds, contributing to the advancement of pharmaceutical research and development.
Used in Agrochemical Development:
In the agrochemical sector, 3-(2,5-dichlorophenyl)-3-oxopropanenitrile is leveraged as a starting material for the creation of new agrochemicals. Its properties make it suitable for the development of products aimed at improving crop health and productivity.
Used in Dye Manufacturing:
3-(2,5-dichlorophenyl)-3-oxopropanenitrile is also utilized in the dye industry as a precursor for the synthesis of various dyes. Its chemical properties enable the production of dyes with specific characteristics, catering to the diverse needs of different applications.

InChI:InChI=1/C9H5Cl2NO/c10-6-1-2-8(11)7(5-6)9(13)3-4-12/h1-2,5H,3H2

Upstream product

• 35112-27-7 ethyl 2,5-dichlorobenzoate 
• 75-05-8 acetonitrile 
• 2476-37-1 2,5-dichloroacetophenone 
• 4571-25-9 2-bromo-1-(2,5-dichlorophenyl)ethanone 
• 143-33-9 sodium cyanide 

Downstream Products

• 1217089-16-1 C₉H₇Cl₂N₃ 
• 934340-33-7 C₁₆H₁₅Cl₂NO₃ 
• 934340-40-6 C₁₅H₁₃Cl₂NO₄ 
• 934340-37-1 C₁₄H₁₁Cl₂NO₄ 
• 934340-24-6 C₁₂H₉Cl₂NO₃ 

Relevant academic research and scientific papers

Design, synthesis, and evaluation of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines as novel PDE-4 inhibitors

Described herein is design, synthesis, and biological evaluation of novel series of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines acting as inhibitors of type 4 phosphodiesterase (PDE4) which is known as a good target for the treatment of asthma and COPD. For this purpose, structure optimization was conducted with the aid of structure-based drug design using the known X-ray crystallography. Also, biological effects of these compounds on the target enzyme were evaluated by using in vitro assays, leading to the potent and selective PDE-4 inhibitor (IC50 10 nM).

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

The C-3 substituents effect on NHE-1 inhibitory activity of (5-arylfuran-2-ylcarbonyl)guanidines, previously identified as potent NHE-1 inhibitors, was investigated. The introduction of amine or alkyl groups at the 3-position of the furan ring, next to the acylguanidine moiety, remarkably improves NHE-1 inhibitory potency. Especially the important finding is that 5-(2,5-dichloro)phenyl and 5-(2-methoxy-5-chloro)phenyl derivatives exhibit high NHE-1 inhibitory activities (IC50 0.02 μM) that match those of 3-unsubstituted derivatives.

Cis-2-benzoyl-3-hydroxy-2-alkenonitriles as anti-inflammatory agents

This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-benozyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.