56759-60-5

Basic information

• Product Name: 2,4,6-tribromo-3,5-dimethylphenol
• Synonyms: 2,4,6-Tribromo-3,5-dimethylphenol
• CAS NO: 56759-60-5
• Molecular Formula: C₈H₇Br₃O
• Molecular Weight: 358.8526
• EINECS: 260-366-4
• Mol File: 56759-60-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 302.9°C at 760 mmHg
• Flash Point: 137°C
• Density: 2.123g/cm³
• Vapor Pressure: 0.000537mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 2,4,6-tribromo-3,5-dimethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-tribromo-3,5-dimethylphenol(56759-60-5)
• EPA Substance Registry System: 2,4,6-tribromo-3,5-dimethylphenol(56759-60-5)

Safety Data

• Hazardous Substances Data: 56759-60-5(Hazardous Substances Data)

Usage

General Description

2,4,6-tribromo-3,5-dimethylphenol is a chemical compound that belongs to the class of phenols and is commonly referred to as tribromophenol. It is a white to off-white crystalline solid and is soluble in organic solvents. 2,4,6-tribromo-3,5-dimethylphenol is used as a disinfectant and preservative in various industrial and commercial products, including wood preservatives, antiseptic creams, and pharmaceuticals. It has antimicrobial properties and is effective against a wide range of microorganisms, making it a valuable ingredient in the formulation of disinfectants and sanitizing products. However, 2,4,6-tribromo-3,5-dimethylphenol has been found to be toxic to aquatic organisms and has been restricted or banned in certain countries due to its potential environmental and health hazards.

Upstream product

• 108-68-9 3,5-Dimethylphenol 
• 1123-09-7 3,5-dimethyl-2-cyclohexen-1-one 
• 7726-95-6 bromine 
• 2320-30-1 3,5-dimethylcyclohexanone 
• 92516-20-6 Ethoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester 
• 92516-26-2 Acetic acid cyano-(4-methoxy-2,6-dimethyl-phenyl)-methyl ester 
• 92516-19-3 2-Ethoxy-2-(4-methoxy-2,6-dimethyl-phenyl)-acetamide 
• 19447-02-0 1-(2,6-dimethyl-4-methoxyphenyl)ethanol 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 92516-42-2 2,4,6-tribromo-3,5-dimethylmethoxybenzene 
• 87405-27-4 2,6-dibromo-3,5-dimethyl-1,4-benzoquinone 
• 854662-48-9 3,5-dibromo-1,4-dimethoxy-2,6-dimethylbenzene 
• 854399-70-5 1-acetoxy-2,6-dibromo-4-diacetylamino-3,5-dimethyl-benzene 
• 872275-58-6 2,6-dibromo-3,5-dimethyl-hydroquinone 
• 856351-98-9 4-amino-2,6-dibromo-3,5-dimethyl-phenol 
• 95111-45-8 2,4,6-tribromo-3,5-dimethyl-4-nitrocyclohexa-2,5-dienone 
• 855411-75-5 2,4,6-tribromo-4-chloro-3,5-dimethyl-cyclohexa-2,5-dienone 
• 855411-61-9 2-bromo-4,4,6-trichloro-3,5-dimethyl-cyclohexa-2,5-dienone 
• 736074-26-3 2,6-dibromo-3,5-dimethyl-4-nitro-phenol 

Relevant articles and documents

Nuclear versus side-chain bromination of 4-methoxy toluene by an electrochemical method

GRAPHICAL ABSTRACT The electrochemical bromination of 4-methoxy toluene by two-phase electrolysis yields 3-bromo 4-methoxy toluene at first, which subsequently undergoes side-chain bromination to give 3-bromo 4-methoxy benzyl bromide as a final product in 86% yield. The two-phase electrolysis consists of 25-50% NaBr as aqueous electrolyte and CHCl3 containing aromatic compound as organic phase. The reaction temperature is maintained at 10-25 °C. The probable orientation of bromine atom in an alkyl aromatic compound (nuclear versus side chain) is explained from the experimental result.

Vanadium-catalyzed oxidative aromatization of 2-cyclohexenones under molecular oxygen

An efficient catalytic oxidative aromatization of 2-cyclohexenones was achieved by a combination of a commercially available inexpensive ligand-free vanadium catalyst, a bromide source, and an acid under atmospheric oxygen to afford the corresponding phenol derivatives. This catalytic oxidative aromatization proceeded even under air. Furthermore, a gram-scale reaction was performed successfully.

Understanding solid/solid organic reactions

The concept of an organic reaction between two macroscopic solid particles is investigated. Thus, we study several reactions that have been recently reported to proceed "in the solid phase" and clearly show that, in most cases, grinding the two solid reactants together results in the formation of a liquid phase. This is true both for catalytic transformations (e.g., aldol condensations and oligomerization of benzylic compounds) and for noncatalytic reactions (Baeyer - Villiger oxidations, oxidative coupling of naphthols using iron chloride, condensation of amines and aldehydes to form azomethines, homo-etherification of benzylic alcohols using p-toluenesulfonic acid, and nuclear aromatic bromination with NBS). This liquefaction implies the existence of a eutectic mixture with Tfusion below ambient temperature (although both reagents have higher than ambient melting points). In cases where heating is required, it is again clear that a phase change (from solid to liquid) occurs, explaining the observed reaction kinetics. On the basis of 19 experimental examples, we discuss the possibility of solid-phase organic reactions and the implications of these findings to the reaction between two solid reagents. A general description of such reactive systems is proposed, based on a consideration of the potential for eutectic (or peritectic) formation between the constituents of the liquid phases that arise during the process of mechanical mixing of the solid reagents and products.