56767-66-9Relevant academic research and scientific papers
Copper-catalyzed aryl amination in aqueous media with 2- dimethylaminoethanol ligand
Lu, Zhikuan,Twieg, Robert J.
, p. 2997 - 3001 (2007/10/03)
Copper-catalyzed amination of aryl bromides and iodides under mild conditions has been developed with 2-dimethylaminoethanol as ligand and water as solvent. A variety of hydrophilic and hydrophobic aryl halide substrates have been aminated in good yield with a variety of amino acids, amino alcohols and peptides. This method has successfully N-arylated some hydrophilic amino compounds not available by other methods.
