5679-59-4Relevant articles and documents
Synthesis and properties of 1,2-dihydro-4(3H)-quinazolinones
Khachatryan,Belus,Misyurin,Baryshnikova,Kolotaev,Matevosyan
, p. 1044 - 1058 (2017/10/31)
We modified the preparative-scale method for the synthesis of 2-aryl 1,2-dihydro-4(3H)-quinazolinone derivatives obtained in high yields by the reaction of new and commercially available aromatic aldehydes with anthranilic acid amides. A series of quinazolinone derivatives possessing anticancer and antiparasitic activities, as well as capable of preventing the progress of neurodegenerative diseases were characterized. There are grounds for clinical trials of these substances in order to select compounds being promising for clinical application.
An efficient route to vinyl substituted oxadiazoles and triazoles using phenylselanyl derivatives as precursor
Wang, Yu-Guang,Huang, Xian,Wu, Yu-Zhou
, p. 7866 - 7873 (2008/02/08)
Vinyl substituted oxadiazoles and triazoles were obtained from selenoxide syn-elimination of phenylselanylethyl substituted oxadiazoles and triazoles, which were prepared through hydrazinolysis, acylation, and cyclocondensation reactions of phenylselanyl-