5679-59-4Relevant academic research and scientific papers
Synthesis and properties of 1,2-dihydro-4(3H)-quinazolinones
Khachatryan,Belus,Misyurin,Baryshnikova,Kolotaev,Matevosyan
, p. 1044 - 1058 (2017/10/31)
We modified the preparative-scale method for the synthesis of 2-aryl 1,2-dihydro-4(3H)-quinazolinone derivatives obtained in high yields by the reaction of new and commercially available aromatic aldehydes with anthranilic acid amides. A series of quinazolinone derivatives possessing anticancer and antiparasitic activities, as well as capable of preventing the progress of neurodegenerative diseases were characterized. There are grounds for clinical trials of these substances in order to select compounds being promising for clinical application.
Novel approach for the synthesis of N-substituted-4-(2-methyl-4-oxo- 4hquinazolin- 3-YL)-butyramides
Amir, Mohammad,Ali, Israr
experimental part, p. 2086 - 2095 (2011/07/31)
A simple and convenient method for the synthesis of N-substituted-4-(2- methyl- 4-oxo-4H-quinazolin-3-yl)-butyramides has been reported. Several aromatic and aliphatic amide derivatives of 4-(2-methyl-4-oxo-4H-quinazolin-3- yl)-butyric acid were prepared
An efficient route to vinyl substituted oxadiazoles and triazoles using phenylselanyl derivatives as precursor
Wang, Yu-Guang,Huang, Xian,Wu, Yu-Zhou
, p. 7866 - 7873 (2008/02/08)
Vinyl substituted oxadiazoles and triazoles were obtained from selenoxide syn-elimination of phenylselanylethyl substituted oxadiazoles and triazoles, which were prepared through hydrazinolysis, acylation, and cyclocondensation reactions of phenylselanyl-
The phosphazo route to 2-alkenamides from acrylic acid and its derivatives
Cabral, Jose,Laszlo, Pierre,Montaufier, Marie-Therese,Lalatiana Randriamahefa
, p. 1705 - 1708 (2007/10/02)
2-Alkenamides are formed in good isolated yields (generally up to 70%) by the reaction of in situ-generated phosphazo compounds issued from aliphatic, alicyclic and aromatic primary amines, with acrylic acid and its derivatives.
