56798-06-2Relevant academic research and scientific papers
An improved synthesis of dichloroalkylphosphonates, chloroalkynes and terminal alkynes via diethyl dichloromethylphosphonate
Carran, John,Waschbuesch, Rachel,Marinetti, Angela,Savignac, Philippe
, p. 1494 - 1498 (1996)
Diethyl 1,1-dichloromethylphosphonate (2) was synthesised in good yield from the reduction of 1,1,1-trichloromethylphosphonate (1) with i-C3H7MgCl and subsequent hydrolysis. The reactivity of 2 towards α-alkylation and its utility in the synthesis of chloroalkynes and terminal alkynes was investigated.
