56824-75-0Relevant academic research and scientific papers
A synthesis of biaryl ketones via the C–S bond cleavage of thiol ester by a Cu/Ag salt
Ghosh, Prasanjit,Ganguly, Bhaskar,Das, Sajal,Perl, Eliyahu
, p. 2751 - 2756 (2017)
We report the synthesis of biaryl ketones via an unprecedented copper/silver catalyzed acylative cross-coupling of thiol esters with either an arylboronic acid or a potassium aryltrifluoroborate. This new method proceeds without a requisite Pd-catalyst and Cu(I)TC mediator, and is efficient, versatile, operationally simple, and accommodating functionally diverse thiol esters, arylboronic acids, and potassium aryltrifluoroborates.
Synthesis of 2-acylthiophenes by palladium-catalyzed addition of thiophenes to nitriles
Jiang, Tao-Shan,Wang, Guan-Wu
supporting information, p. 369 - 373 (2014/05/20)
A direct synthesis of 2-acylthiophenes has been developed through palladium-catalyzed addition of thiophenes to nitriles. The reaction proceeded well under the palladium(II) acetate/2,2'-bipyridine system and using d-(+)-camphorsulfonic acid as the additive. In addition, the obtained 2-acylthiophenes could undergo further coupling reactions to generate novel products.
