56839-43-1 Usage
Description
Eperisone hydrochloride, also known by the brand name MYONAL, is a centrally acting muscle relaxant that is structurally related to Tolperisone (T535475). It is a white solid and is used in the management of various spastic conditions such as cervical spondylosis and cerebral palsy.
Uses
Used in Pharmaceutical Industry:
Eperisone hydrochloride is used as a spasmolytic agent for its muscle relaxant properties, particularly in the skeletal system. It helps in the management of spastic conditions like cervical spondylosis and cerebral palsy.
Used as an Antispasmodic:
Eperisone hydrochloride is used as an antispasmodic agent, providing relief from muscle spasms and cramps, which can be beneficial in various medical conditions and treatments.
Manufacturing Process
To 60 ml of isopropanol, there are introduced 120 g of 4-ethyl-propiophenone,
28.8g of p-formaldehyde and 107 g of piperidine hydrochloride, and the
resulting mixture is heated to reflux on an oil bath with stirring. The heating is
continued, and when the reaction mixture solidifies, the state being a sign of
completion of the reaction, there are added 500 ml of acetone thereinto. The
solidified mass is pulverized by crush, recovered by filtration and washed with
acetone. 144 g of the crude dry crystalline substance is thus obtained, which
is the hydrochloride of the purposed product. The hydrochloride is
recrystallized from isopropanol, and there are obtained the crystalline needles
having the melting point of 170°C to 172°C.
Therapeutic Function
Muscle relaxant
Check Digit Verification of cas no
The CAS Registry Mumber 56839-43-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,8,3 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 56839-43:
(7*5)+(6*6)+(5*8)+(4*3)+(3*9)+(2*4)+(1*3)=161
161 % 10 = 1
So 56839-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H25NO.ClH/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18;/h7-10,14H,3-6,11-13H2,1-2H3;1H
56839-43-1Relevant articles and documents
Preparation method of Eperisone hydrochloride impurity F
-
, (2021/02/25)
The invention provides a preparation method of Eperisone hydrochloride impurity F, which comprises the following steps: 2-bromoethylbenzene is used as a raw material, 1- (2-ethylphenyl) propanol is obtained through Grignard reaction, 2-ethyl propiophenone is obtained through oxidation reaction, and finally the Eperisone hydrochloride impurity F is obtained through Mannich reaction of the 2-ethyl propiophenone, paraformaldehyde and piperidine hydrochloride by a one-pot method. The structure of the Eperisone hydrochloride impurity F is shown as a formula (I), the purity of theEperisone hydrochloride impurity F obtained by adopting the technical scheme provided by the invention can reach 99%, and the Eperisone hydrochloride impurity F can be used as a reference substance for experimental research.