56843-79-9

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-2-METHYL-THIENO[2,3-D]PYRIMIDINE is used as a building block for the synthesis of various pharmaceutical compounds. Its potent biological activities contribute to the development of drugs with therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 4-CHLORO-2-METHYL-THIENO[2,3-D]PYRIMIDINE is utilized as a starting material for the production of herbicides. Its incorporation into these compounds helps in the control of unwanted plant growth, thereby enhancing crop productivity.
Used in Medicinal Chemistry Research:
4-CHLORO-2-METHYL-THIENO[2,3-D]PYRIMIDINE is employed as a research tool in medicinal chemistry. Its unique structure and reactivity allow scientists to explore new chemical pathways and synthesize novel compounds with potential therapeutic applications.
Used in Synthetic Organic Chemistry:
4-CHLORO-2-METHYL-THIENO[2,3-D]PYRIMIDINE is also used in synthetic organic chemistry, where its reactivity and structural features facilitate the development of new synthetic routes and the creation of innovative organic molecules with diverse applications.

InChI:InChI=1/C7H5ClN2S/c1-4-9-6(8)5-2-3-11-7(5)10-4/h2-3H,1H3

Upstream product

• 21582-51-4 2-methylthieno[2,3-d]pyrimidin-4(3H)-one 
• 55654-18-7 N-(3-cyanothiophen-2-yl)acetamide 
• 21582-51-4 2-methylthieno[2,3-d]pyrimidin-4-ol 
• 4651-82-5 2-amino-3-cyanothiophene 
• 4651-81-4 Methyl 2-aminothiophene-3-carboxylate 
• 31891-06-2 ethyl 2-aminothiophene-3-carboxylate 

Downstream Products

• 1621366-56-0 N-(2-ethylphenyl)-3-methyl-5-[(2-methylthieno[2,3-d]pyrimidin-4-yl)amino]-1,2-thiazole-4-carboxamide 
• 898044-21-8 C₂₅H₂₉N₇O₂S 
• 56844-01-0 2-methyl-thieno[2,3-d]pyrimidine 

Relevant academic research and scientific papers

THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS

The present disclosure provides compounds, methods, and compositions which may be used to treat tuberculosis. In some embodiments, these compounds and compositions have a bactericidal property against Mycobacterium tuberculosis (Mtb). Methods of employing such agents are also provided.

MONOCYCLIC, THIENO, PYRIDO, AND PYRROLO PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE OF THE SAME

The present invention provides monocyclic, thieno, pyrido and pyrrolo pyrimidine compounds. Pharmaceutical compositions comprising one or more of these compounds and optionally comprising a pharmaceutically acceptable salt or hydrate of one or more of the compounds are provided. Preferably, these pharmaceutical compositions further comprise at least one pharmaceutically acceptable carrier. Methods of treating a patient having cancer are provided wherein a therapeutically effective amount of one or more of these compounds or pharmaceutical compositions are administered to the patient.

Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold

From 4 antiplasmodial hit-molecules identified in 2-trichloromethylquinazoline series, we conducted a global Structure-Activity relationship (SAR) study involving 26 compounds and covering 5 molecular regions (I – V), aiming at defining the corresponding

N-ALKYL-N-ARYL-THIENOPYRIMIDIN-4-AMINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF

Disclosed are N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs thereof, represented by the Formulae I-II: wherein Ar, R1 -R4 and R10 are defined herein. The present invention relates to the discovery that compounds havi