56872-27-6

Basic information

• Product Name: 1-BENZYLOXY-4-BROMO-2-CHLOROBENZENE
• Synonyms: 1-BENZYLOXY-4-BROMO-2-CHLOROBENZENE;4-BroMo-2-chloro-1-(phenylMethoxy)-benzene
• CAS NO: 56872-27-6
• Molecular Formula: C₁₃H₁₀BrClO
• Molecular Weight: 297.5749
• Product Categories: Organic Building Blocks;Oxygen Compounds;Protected Alcohols/Phenols;Aromatics;Heterocycles;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Protected Alcohols/Phenols
• Mol File: 56872-27-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 58-62 °C
• Boiling Point: 366.808°C at 760 mmHg
• Flash Point: 175.639°C
• Appearance: /
• Density: 1.471g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 1-BENZYLOXY-4-BROMO-2-CHLOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYLOXY-4-BROMO-2-CHLOROBENZENE(56872-27-6)
• EPA Substance Registry System: 1-BENZYLOXY-4-BROMO-2-CHLOROBENZENE(56872-27-6)

Safety Data

• Hazard Codes: Xi,N
• Statements: 37/38-41-50/53
• Safety Statements: 26-36/37/39-60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 56872-27-6(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

InChI:InChI=1/C13H10BrClO/c14-11-6-7-13(12(15)8-11)16-9-10-4-2-1-3-5-10/h1-8H,9H2

Upstream product

• 3964-56-5 4-bromo-2-chlorophenol 
• 100-44-7 benzyl chloride 
• 95-57-8 2-monochlorophenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 220214-82-4 3-[(4-benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 197778-01-1 3-[(4-benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 1059705-66-6 C₁₈H₂₁ClN₂O 
• 85474-76-6 4-Hydroxy-m-chlorophenylpiperazine 
• 871338-83-9 1,1-dimethylethyl 4-[3-chloro-4-(2-morpholin-4-yl-ethoxy)phenyl]piperazine-1-carboxylate 
• 871464-68-5 4-[2-(2-chloro-4-piperazin-1-ylphenoxy)ethyl]morpholine 
• 871338-82-8 1,1-dimethylethyl 4-(3-chloro-4-hydroxyphenyl)-piperazine-1-carboxylate 
• 220214-84-6 (2R,3R)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidenepropan-1-ol 
• 220214-80-2 (S)-3-[(S)-(4-Benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 220214-86-8 (R)-3-[(R)-(4-Benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 220214-81-3 (2S)-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidene-3-oxopropan-1-ol 
• 220214-85-7 3-(4-benzyloxy-3-chloro-benzoyl)-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 220214-87-9 (2R,3R)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylaminopropan-1-ol 
• 197777-97-2 (2S,3S)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidenepropan-1-ol 

Relevant articles and documents

Phosphoramidate prodrug of nucleoside analogues, a pharmaceutical composition and applications of the phosphoramidate prodrug

The invention relates to phosphoramidate prodrug of nucleoside analogues, or stereoisomers of the phosphoramidate prodrug, or a mixture of the stereoisomers of the phosphoramidate prodrug, or pharmaceutically acceptable salts or solvates of the phosphoramidate prodrug, and applications in the preparation of medicine for preventing or treating hepatitis B virus (HBV) and/or human immunodeficiency virus (HIV) infection alone or in combination with other medicine. The anti-HBV activity of the compound of the invention is equivalent to that of tenofovir alafenamide fumarate (TAF), and the compoundof the invention has the anti-liver fibrosis effect, can help improve the therapeutic effect of patients, and has good safety important clinical significance.

NOVEL OLEFIN DERIVATIVE

The object of the present invention is to provide novel compounds having ACC2 inhibiting activity. In addition, the object of the present invention is to provide a pharmaceutical composition comprising the compound. A compound of formula (I′): wherein R1 is substituted or unsubstituted aryl etc., R2 is each independently hydrogen, substituted or unsubstituted alkyl etc., R3 is each independently hydrogen, substituted or unsubstituted alkyl etc., n is an integer from 0 to 3, R12 is hydrogen, substituted or unsubstituted alkyl etc., Ring A is aromatic carbocycle or aromatic heterocycle, R9 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl etc., m is an integer from 0 to 4, R4 and R5 is each independently hydrogen, substituted or unsubstituted alkyl etc., R6 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl etc., R13 is hydrogen, substituted or unsubstituted alkyl etc., X5 is bond etc., R7 is hydrogen or substituted or unsubstituted alkyl, R8 is substituted or unsubstituted alkylcarbonyl, substituted or unsubstituted alkenylcarbonyl etc.

PESTICIDAL SUBSTITUTED PHENYLETHERS

The invention relates to the use of phenylether derivatives of formula (I), to compositions thereof for the control of pests, including arthropods and helminths.