569332-73-6Relevant academic research and scientific papers
Amide synthesis: Via nickel-catalysed reductive aminocarbonylation of aryl halides with nitroarenes
Cheung, Chi Wai,Leendert Ploeger, Marten,Hu, Xile
, p. 655 - 659 (2018/01/28)
Aminocarbonylation of aryl halides is one of the most useful methods in amide synthesis, but nitroarenes have not been used as a nitrogen source in this method even though they are more economical and accessible than anilines. Reported here is the development of nickel catalysis for the first three-component reactions of aryl halides, Co2(CO)8, and nitroarenes under reductive conditions to produce aryl amides. A wide range of (hetero)aryl iodides and bromides as well as nitro(hetero)arenes are suitable reaction partners, and high functional group compatibility has been achieved. The method might be used for the streamlined synthesis of aryl amides.
A PHARMACEUTICAL COMPOSITION COMPRISING AN AMIDE DERIVATIVE
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Page/Page column 67-68, (2008/06/13)
The present invention provides a novel modulator of the TRPV1-receptor function, comprising a compound of the formula; wherein ring A is an optionally substituted carbocycle or heterocycle, ring B is an optionally substituted benzene ring or an optionally
Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
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Page/Page column 10, (2008/06/13)
The present invention relates to compounds of formula (I) that are novel VR1 antagonists useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence, or bladder overactivity.
Pharmaceutical compositions containing phenylamides
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, (2008/06/13)
Pharmaceutical compositions for inhibiting the aggregation of erthyrocytes or thrombocytes which include phenylamides which conform to the formula: STR1 with R1-6, X, A and B being as defined. Processes for the preparation of novel phenylamides
