56935-39-8Relevant academic research and scientific papers
Catalytic enantioselective desymmetrization of cyclobutane-1,3diones by carbonyl-amine condensation
Wen, Kai-Ge,Liu, Chao,Wei, Dong-Hui,Niu, Yan-Fei,Peng, Yi-Yuan,Zeng, Xing-Ping
supporting information, p. 1118 - 1122 (2021/02/16)
A chiral phosphoric acid-catalyzed enantioselective condensation of 2,2-disubstituted cyclobutane-1,3-diones with a primary amine is described. This reaction offered a mild and efficient protocol for constructing quaternary carbon-containing cyclobutanes
A simple method for the synthesis of 2-amino-1(4′-methoxyphenyl)-propane
Mereyala,Koduru
, p. 3005 - 3010 (2007/10/03)
Synthesis of 2-amino-1-(4′-methoxyphenyl)-propane (II) starting from p-anisaldehyde (1) in 67% overall yield is described. Key reactions involved Horner-Wadswoth-Emmons olefination of 1 to form the ester 2 and Hoffmann degradation of amide 5 to obtain the amine II.
Convenient Synthetic Sequence for the Preparation of Indanones
Smonou, Ioulia,Orfanopoulos, Michael
, p. 1387 - 1397 (2007/10/02)
A convenient and general methods is reported for the synthesis of indanones from aryl ketones or aldehydes.
Syntheses of 5-, 7-, and 8-Methoxy-3-methyl-2-tetralone
Johansson, Anette M.,Mellin, Charlotta,Hacksell, Uli
, p. 5252 - 5258 (2007/10/02)
Two efficient syntheses of 5-methoxy- and 8-methoxy-3-methyl-2-tetralone and the synthesis of the 7-methoxy isomer via a different route are described.Also reported is the synthesis of 8-methoxy-3,3-dimethyl-2-tetralone.The regioselectivity of lithium carbanion formation in 1,6-, 1,7-, and 2,7-dihydroxynaphthalene is discussed.The latter compound undergoes dimetalation more easily than the other isomers.
