5694-47-3

Usage

Uses

Used in Perfumery Industry:
2,2-Dimethyl-1,3-dithiolane-4-methanol is used as a fragrance ingredient for its strong, fruity scent, contributing to the creation of various perfumes and enhancing their olfactory profiles.
Used in Food Industry:
In the food industry, 2,2-Dimethyl-1,3-dithiolane-4-methanol is used as a flavoring agent to impart a pleasant aroma to a variety of food products, thereby enhancing their sensory appeal.
Used as a Solvent:
2,2-Dimethyl-1,3-dithiolane-4-methanol is utilized as a solvent in certain chemical processes due to its ability to dissolve specific substances, facilitating reactions and extractions.
Used in Chemical Synthesis:
As a building block in the synthesis of other chemical compounds, 2,2-Dimethyl-1,3-dithiolane-4-methanol plays a crucial role in the production of various organic and inorganic chemicals, contributing to the diversity of chemical products available.
It is important to handle 2,2-Dimethyl-1,3-dithiolane-4-methanol with care, storing it in a cool, dry place, and keeping it away from sources of ignition to ensure safety during its use in different applications.

InChI:InChI=1/C6H12OS2/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3

Upstream product

• 59-52-9 2,3-dimercaptopropanol 
• 67-64-1 acetone 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 6008-74-8 4-(chloromethyl)-2,2-dimethyl-1,3-dithiolane 

Relevant academic research and scientific papers

Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents

Sigma receptors (SRs) are recognized as valuable targets for the treatment of neurodegenerative disorders. A series of novel SRs ligands were designed by combining key pharmacophoric amines (i.e., benzylpiperidine or benzylpiperazine) with new 1,3-dithiolane-based heterocycles and their bioisosters. The new compounds exhibited a low nanomolar affinity for sigma-1 and sigma-2 receptors. Five selected compounds were evaluated for their neuroprotective capacity on SH-SY5Y neuroblastoma cell line. They were able to counteract the neurotoxicity induced by rotenone, oligomycin and NMDA. Competition studies with PB212, a S1R antagonist, confirmed the involvement of S1R in neuroprotection from the oxidative stress induced by rotenone. Electrophysiological experiments performed on cortical neurons in culture highlighted the compounds ability to reduce NMDA-evoked currents, suggesting a negative allosteric modulator activity toward the NMDA receptor. Altogether these results qualify our novel dithiolane derivatives as potential agents for fighting neurodegeneration.

Herbicidal 1-aryl-delta2-1,2,4-triazolin-5-ones

Aryltriazolinones of the formula STR1 in which W is oxygen or sulfur; X1 and X2 are independently selected from halogen, haloalkyl, and alkyl; R is a three- to eight-membered ring heterocyclic group of one or two, same or different, ring heteroatoms selected from oxygen, sulfur, and nitrogen, or an alkyl radical substituted with said heterocyclic group; R1 is alkyl, haloalkyl, cyanoalkyl, alkenyl, alkynyl, or a group of the formula -alkyl-Y--R3 ; R2 is halogen, alkyl, cyanoalkyl, haloalkyl, arylalkyl, or a group of the formula -alkyl-Y--R3 ; R3 is alkyl, alkenyl, or alkynyl; and Y is oxygen or S(O)r in which r is 0 to 2 are disclosed and exemplified.

Comparative radioprotective activity of various pentagonal compounds with two heteroatomes

Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.