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N-Ethyl-N'-hydroxyurea, also known as NEtHU, is an organic compound with the chemical formula C3H8N2O2. It is a derivative of hydroxyurea, where one of the hydrogen atoms on the nitrogen atom is replaced by an ethyl group. NEtHU is a white crystalline solid that is soluble in water and has been studied for its potential use as a chemotherapeutic agent. It works by inhibiting ribonucleotide reductase, an enzyme involved in DNA synthesis, thereby disrupting the cell cycle and preventing cancer cell proliferation. Due to its ability to target rapidly dividing cells, NEtHU has been investigated for its potential in treating various types of cancer, including leukemia and solid tumors. However, its use in clinical settings is limited due to its toxicity and side effects, which include bone marrow suppression and gastrointestinal issues.

5710-11-2

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5710-11-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5710-11-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,1 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5710-11:
(6*5)+(5*7)+(4*1)+(3*0)+(2*1)+(1*1)=72
72 % 10 = 2
So 5710-11-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H8N2O2/c1-2-4-3(6)5-7/h7H,2H2,1H3,(H2,4,5,6)

5710-11-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ethyl-3-hydroxyurea

1.2 Other means of identification

Product number -
Other names N-ethyl-N'-hydroxyurea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5710-11-2 SDS

5710-11-2Upstream product

5710-11-2Relevant academic research and scientific papers

N-substituted hydroxyureas as urease inhibitors

Uesato, Shinichi,Hashimoto, Yuichiro,Nishino, Masaru,Nagaoka, Yasuo,Kuwajima, Hiroshi

, p. 1280 - 1282 (2007/10/03)

In order to seek a urease inhibitor more potent than hydroxyurea (1), its alkyl- or phenyl-substituted derivatives were synthesized and evaluated for their effect on the jack bean urease. Of 16 compounds tested, m-methyl-(10) and m-methoxy-phenyl substituted hydroxyurea (13) showed the most potent inhibitory activities against the enzyme.

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