57102-98-4

Basic information

• Product Name: 9-ETHYL-9 H-CARBAZOLE-3-CARBOXYLIC ACID
• Synonyms: RARECHEM AL BE 0085;9-ETHYL-9 H-CARBAZOLE-3-CARBOXYLIC ACID;9-ethyl-3-carbazolecarboxylic acid;9-ethylcarbazole-3-carboxylic acid;ZERO/005445
• CAS NO: 57102-98-4
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.27
• Mol File: 57102-98-4.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 9-ETHYL-9 H-CARBAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 9-ETHYL-9 H-CARBAZOLE-3-CARBOXYLIC ACID(57102-98-4)
• EPA Substance Registry System: 9-ETHYL-9 H-CARBAZOLE-3-CARBOXYLIC ACID(57102-98-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 57102-98-4(Hazardous Substances Data)

Usage

Uses

9-Ethyl-9H-carbazole-3-carboxylic Acid is a useful reagent for the preparation of an oxime ester photoinitiator.

Upstream product

• 124-38-9 carbon dioxide 
• 57103-07-8 9-ethyl-3,6-diiodocarbazole 
• 57103-00-1 9-ethyl-9H-carbazole-3-carbonitrile 
• 86-28-2 N-ethylcarbazole 
• 68-12-2 N,N-dimethyl-formamide 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 62-53-3 aniline 
• 4058-18-8 methyl 4-(phenylamino)benzoate 
• 97931-41-4 3-methoxycarbonylcarbazole 
• 773873-63-5 N-ethylcarbazole-3-methyl formate 
• 86-74-8 9H-carbazole 
• 7570-45-8 N-ethyl-3-carbazolealdehyde 
• 1484-04-4 N-ethyl-3-acetylcarbazole 
• 64-67-5 diethyl sulfate 

Downstream Products

• 432506-50-8 9-ethyl-9H-carbazole-3-carboxylic acid phenylethylamide 
• 432505-71-0 9-Ethyl-9H-carbazole-3-carboxylic acid benzylamide 
• 302557-11-5 N-ethyl-3-(ω-aminopentylaminocarbonyl)-carbazole 

Relevant articles and documents

Tert -Butylhydroperoxide-Mediated Oxidation of Carbazole-3-carboxyaldehydes

Oxidation of carbazole-3-carboxyaldehydes promoted by a 70% aqueous solution of tert -butylhydroperoxide leads to the corresponding carbazole-3-carboxylic acids in good yields. This transition-metal-free oxidation protocol is attractive for the synthesis of pharmaceutically important carbazole analogues.

MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS

This disclosure relates to compounds that target microtubules, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases. More particularly, this disclosure relates to modified carbazole compounds and pharmaceutical compositions thereof, methods of targeting microtubules with these compounds, and methods of treating diseases affected by microtubule disruption.

Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles

A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.