57148-29-5

Upstream product

• 108-30-5 succinic acid anhydride 
• 7005-72-3 4-chlorodiphenyl ether 
• 66549-02-8 α-(3-fluorophenyl)-4-morpholineacetonitrile 
• 69797-46-2 4-(3'-fluorophenyl)-4-oxo-butanoic acid 
• 106-48-9 4-chloro-phenol 

Downstream Products

• 57148-32-0 4-<4-(4-chlorophenoxy)phenyl>butyric acid 
• 73980-34-4 3-Bromo-4-[4-(4-chloro-phenoxy)-phenyl]-4-oxo-butyric acid 
• 73980-30-0 (trans)-3-<4-(4-chlorophenoxy)benzoyl>acrylic acid 
• 97220-95-6 3-acetylthio-3-<4-(4-chlorophenoxy)benzoyl>propionic acid 
• 97220-50-3 3-<4-(chlorophenoxy)benzoyl>-3-mercaptopropionic acid 

Relevant academic research and scientific papers

Antihypertensive Agents: Angiotensin Converting Enzyme Inhibitors. 1--L-prolines

A series of 1--L-proline derivatives was synthesized.A number of these compounds are potent angiotensin converting enzyme (ACE) inhibitors that lowered blood pressure in aorta-coarcted renal hypertensive rats.The most active

Studies on antihyperlipidemic agents. I. Synthesis and hypolipidemic activities of phenoxyphenyl alkanoic acid derivatives

The alkanoic acids containing phenoxyphenyl moiety at ω-position were prepared and tested for hypolipidemic property. Some of the compounds showed hypoglycemic activity besides hypolipolipidemic one. Further study on the selected compound, 3-[4-(4-chlorophenoxy)benzoyl]propionic acid (8) revealed that it increased insulin sensitivity of adipose tissue of obese and diabetic mice (KKA(y)). The structure-activity relationship was discussed briefly.