57159-62-3 Usage
Description
3-(2-bromoacetamido)propanoic acid NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 57159-62-3 differently. You can refer to the following data:
1. A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent.
Spacer Arm: 6.2 Angstroms
2. A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 6.2 Angstroms
Check Digit Verification of cas no
The CAS Registry Mumber 57159-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,1,5 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57159-62:
(7*5)+(6*7)+(5*1)+(4*5)+(3*9)+(2*6)+(1*2)=143
143 % 10 = 3
So 57159-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H11BrN2O5/c10-5-6(13)11-4-3-9(16)17-12-7(14)1-2-8(12)15/h1-5H2,(H,11,13)
57159-62-3Relevant articles and documents
ANTIMICROBIAL VACCINE COMPOSITIONS
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Paragraph 0078, (2021/03/05)
This invention is directed to antimicrobial vaccine compounds and compositions comprising oligosaccharide β-(1→6)- glucosamine groups having from 3 to 12 glucosamine units linked through a linker group to tetanus toxoid wherein the toxoid is primarily in
New heterobifunctional cross-linking reagents for protein conjugation, N-(bromoacetamido-n-alkanoyloxy)succinimides.
Zaitsu,Ohnishi,Hosoya,Sugimoto,Ohkura
, p. 1991 - 1997 (2007/10/02)
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