57194-39-5

Basic information

• Product Name: methyl 4-(acetyloxy)-15-[5-ethyl-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
• CAS NO: 57194-39-5
• Molecular Formula: C₄₆H₅₈N₄O₈
• Molecular Weight: 794.9747
• Mol File: 57194-39-5.mol
• Article Data: 2

Chemical Properties

• Density: 1.34g/cm³
• Refractive Index: 1.66
• CAS DataBase Reference: methyl 4-(acetyloxy)-15-[5-ethyl-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(acetyloxy)-15-[5-ethyl-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate(57194-39-5)
• EPA Substance Registry System: methyl 4-(acetyloxy)-15-[5-ethyl-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate(57194-39-5)

Safety Data

• Hazardous Substances Data: 57194-39-5(Hazardous Substances Data)

Upstream product

• 38390-45-3 15'20'-anhydrovinblastine 
• 109704-84-9 C₅₃H₆₅N₄O₈⁽¹⁺⁾*C₇H₇O₃S^(1-) 
• 2182-14-1 vindoline 
• 109704-80-5 N^b-benzyl-21-(tosyloxy)-D-seco-Ψ-vincadifformine 
• 121074-32-6 (R)-4-[(S)-2-(Toluene-4-sulfonyloxymethyl)-butyl]-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylic acid methyl ester 
• 109704-79-2 N^b-benzyl-21-hydroxy-D-seco-Ψ-vincadifformine 
• 121074-33-7 (2R,3aS,10bR,12bS)-5-Chloro-2-ethyl-2,3,3a,4,5,11,12,12b-octahydro-1H-6,12a-diaza-indeno[7,1-cd]fluorene-5-carboxylic acid methyl ester 
• 73836-92-7 (+/-)-20-Epipseudovincadifformine 
• 74526-89-9 C₄₆H₅₆N₄O₈ 

Relevant articles and documents

Syntheses of 20'-Deoxyvinblastine, 20'-Deoxyleurosidine, 20'-Deoxyvincovaline, 20'-epi-20'-Deoxyvincovaline, and 20'-Deoxyvincristine and Its 20'-Epimer through Racemic and Enantioselectively Generated Intermediates. New Syntheses of D/E-cis- and -trans-Ψ

Vindoline (20), on reaction with chloro imine derivatives of the D-seco-D/E-trans-Ψ- and -20-epi-Ψ-vincadifformines 18 and 19, followed by cyclization and debenzylation steps, provided the natural products 20'-deoxyvinblastine (4) and 20'-deoxyleurosidine