57196-70-0Relevant articles and documents
Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2- dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted xanthine derivatives
Bandyopadhyay, Prabal,Sathe, Manisha,Sharma, Pratibha,Kaushik
, p. 4631 - 4635 (2012/09/05)
Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed
A mild method for the preparation of 8-substituted xanthines from 5,6- diaminouracils
De Araujo, Aline D.,Bacher, Edmond,Joachim Demnitz,Santos, Douglas A.
, p. 29 - 36 (2007/10/03)
The Schiff base derivatives (3), prepared from the respective 5,6- diaminouracil (1) and aldehydes can be mildly oxidatively cyclized with m- CPBA in MeCN to afford C-8 substituted xanthines (6).
Synthesis and in vitro bronchospasmolytic activity of 8-aryl, heteroaryl or arylalkyl theophyllines
Baziard-Mouysset, G.,Rached, A.,Younes, S.,Tournaire, C.,Stigliani, J. L.,et al.
, p. 253 - 260 (2007/10/02)
Twenty-four 8-aryl- or 8-heteroaryl-substituted theophyllines have been synthesized.The substituents are aromatic rings and heterocycles likely to induce an antiallergic effect or a spasmolytic activity.In vitro evaluation of the bronchospasm caused by ac
Reaction of 6-Arylidenehydrazino-1,3-dimethyluracils with Thionyl Chloride Leading to Purine, Thiazolopyrimidine, Pyrimidothiadiazine, Pyrazolopyrimidine, and Thiadiazolopyrimidine Derivatives
Ichiba, Misuzu,Senga, Keitaro
, p. 381 - 384 (2007/10/02)
The reaction of 6-arylidenehydrazino-1,3-dimethyluracils with thionyl chloride in benzene afforded purine, thiazolopyrimidine, pyrimidothiadiazine, pyrazolopyrimidine, and thiadiazolopyrimidine derivatives, while
Pyrimidine Derivatives and Related Compounds. Part 47. A New Synthesis of Xanthines and Pyrrolopyrimidines by Intramolecular Cyclisation of 6-Substituted 5-Nitrouracil Derivatives
Hirota, Kosaku,Sugiyama, Tadashi,Kitade, Yukio,Senda, Shigeo,Maki, Yoshifumi
, p. 583 - 588 (2007/10/02)
6-Arylalkylamino-1,3-dimethyl-5-nitrouracils (2a-f) were prepared by reaction of 6-chloro-1,3-dimethyl-5-nitrouracil (1) with arylalkylamines in the presence of triethylamine.Among them, the 6-arylalkylaminouracils (2a-d), possessing no substituent at the