57224-14-3

Usage

Uses

Used in Pharmaceutical Industry:
2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI) is used as a starting material for the synthesis of various bioactive molecules, making it valuable in the development of new drugs and pharmaceuticals.
Used in Chemical Industry:
2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI) is used as a building block for the synthesis of diverse organic compounds, contributing to the creation of a wide range of chemical products.

Upstream product

• 2133-40-6 L-proline methyl ester monohydrochloride 

Downstream Products

• 85213-22-5 2-acetyl-1-pyrrolidine 
• 79068-32-9 3-<1,2-Bis(benzyloxycarbonyl)hydrazino>-1-pyrrolin-2-carbonsaeure-methylester 
• 72978-22-4 methyl N-benzyloxycarbonyl-4,5-dihydropyrrole-2-carboxylate 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 79068-31-8 methyl 3-hydroxy-1H-pyrrol-2-yl-carboxylate 
• 79068-33-0 3-<1,2-Bis(ethoxycarbonyl)hydrazinol>-1-pyrrolin-2-carbonsaeure-methylester 
• 79068-30-7 3-<1,2-Bis(ethoxycarbonyl)hydrazino>-2-pyrrolcarbonsaeure-methylester 
• 79068-34-1 3-Acetoxy-1-pyrrolin-2-carbonsaeure-methylester 
• 89019-22-7 1,6-diazabicyclo<3.1.0>hexane-5-carboxylic acid methyl ester 
• 41222-64-4 12,13-dehydroprolyl-2-(1,1-dimethylallyltryptophyl)diketopiperazine 
• 609-36-9 rac-Pro-OH 
• 79067-97-3 trans-1-Acetyl-3-triphenylmethylthio-2-pyrrolidincarbonsaeure 
• 79067-98-4 cis-1-Acetyl-3-phenylthio-2-pyrrolidincarbonsaeure-methylester 
• 79067-98-4 trans-1-Acetyl-3-phenylthio-2-pyrrolidincarbonsaeure-methylester 

Relevant academic research and scientific papers

Photooxidative decarboxylation of proline, a novel oxidative stress to natural amines

Proline was decarboxylated quantitatively to Δ1-pyrroline on photoirradiation in the presence of rose bengal, while its methyl ester yielded an equimolar mixture of Δ1- and Δ5-pyrroline-2-carboxylic acid methyl esters. The decarboxylation of proline took place under either an aerobic (O2 bubbling) or an anaerobic (N2 bubbling) conditions, and under the latter condition, extent of the reaction depended on the amount of rose bengal employed. These results imply mechanistically that the reaction is the Type I photooxidation, indicating a new type of oxidative stress to natural secondary amines.