57224-14-3

Basic information

• Product Name: 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)
• Synonyms: 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)
• CAS NO: 57224-14-3
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127.14116
• Product Categories: ACIDHALIDE
• Mol File: 57224-14-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 184.4±23.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• PKA: 5.32±0.20(Predicted)
• CAS DataBase Reference: 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)(57224-14-3)
• EPA Substance Registry System: 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)(57224-14-3)

Safety Data

• Hazardous Substances Data: 57224-14-3(Hazardous Substances Data)

Usage

General Description

The chemical 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI) is a compound that belongs to the class of pyrrole derivatives. It is a methyl ester of 3,4-dihydro-2H-pyrrole-5-carboxylic acid and is commonly used in the pharmaceutical and chemical industry. 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI) has potential applications in medicinal chemistry, where it can be used as a starting material for the synthesis of various bioactive molecules. Its properties and reactivity make it a valuable building block for the synthesis of diverse organic compounds. Furthermore, its methyl ester form allows for greater solubility and flexibility in reaction conditions, making it suitable for a wide range of synthetic processes.

Upstream product

• 2133-40-6 L-proline methyl ester monohydrochloride 

Downstream Products

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• 79067-98-4 cis-1-Acetyl-3-phenylthio-2-pyrrolidincarbonsaeure-methylester 
• 79067-98-4 trans-1-Acetyl-3-phenylthio-2-pyrrolidincarbonsaeure-methylester 
• 79068-15-8 trans-3-(Phenylthio)prolin 
• 79068-26-1 cis-3-Acetoxyprolin 
• 79068-18-1 trans-3-(Ethylthio)prolin 
• 79068-20-5 trans-3-Mercaptoprolin 
• 79068-27-2 trans-3-<1,2-Bis(benzyloxycarbonyl)hydrazino>prolin 
• 89019-23-8 5-N-Methylcarbomoyl-1,6-diazabicyclo<3.1.0>hexane 
• 89019-25-0 endo-5-N-Methylcarbomoyl-6-chloro-1,6-diazabicyclo<3.1.0>hexane 
• 89019-22-7 1,6-diazabicyclo<3.1.0>hexane-5-carboxylic acid methyl ester 
• 1193-62-0 methyl Pyrrole-2-carboxylate 

Relevant articles and documents

Photooxidative decarboxylation of proline, a novel oxidative stress to natural amines

Proline was decarboxylated quantitatively to Δ1-pyrroline on photoirradiation in the presence of rose bengal, while its methyl ester yielded an equimolar mixture of Δ1- and Δ5-pyrroline-2-carboxylic acid methyl esters. The decarboxylation of proline took place under either an aerobic (O2 bubbling) or an anaerobic (N2 bubbling) conditions, and under the latter condition, extent of the reaction depended on the amount of rose bengal employed. These results imply mechanistically that the reaction is the Type I photooxidation, indicating a new type of oxidative stress to natural secondary amines.