57233-86-0

Basic information

• Product Name: (S)-1-(4-Nitrophenyl)ethylamine hydrochloride
• Synonyms: (R)-(-)-1-(4-NITROPHENYL)-ETHYLAMINE HCL;(R)-1-(4-NITROPHENYL)ETHYLAMINE HYDROCHLORIDE;(R)-4-NITROPHENYL-1-ETHYLAMINE HYDROCHLORIDE;(R)-(-)-ALPHA-METHYL-4-NITROBENZYLAMINE HCL;(R)-ALPHA-METHYL-4-NITROBENZYLAMINE HYDROCHLORIDE;(R)-(+)-ALPHA-METHYL-4-NITROBENZYLAMMONIUM CHLORIDE;(R)-A-METHYL-4-NITROBENZYLAMINE HCL;(R)-(+)-A-METHYL 4-NITROBENZYLAMINE HYDROCHLORIDE
• CAS NO: 57233-86-0
• Molecular Formula: C₈H₁₀N₂O₂*ClH
• Molecular Weight: 202.64
• Mol File: 57233-86-0.mol

Chemical Properties

• Melting Point: 248-250 °C(lit.)
• Boiling Point: 321.3 °C at 760 mmHg
• Flash Point: 148.1 °C
• Appearance: /
• Vapor Pressure: 0.000219mmHg at 25°C
• Storage Temp.: Store below +30°C.
• BRN: 3701567
• CAS DataBase Reference: (S)-1-(4-Nitrophenyl)ethylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-Nitrophenyl)ethylamine hydrochloride(57233-86-0)
• EPA Substance Registry System: (S)-1-(4-Nitrophenyl)ethylamine hydrochloride(57233-86-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 57233-86-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H10N2O2.ClH/c1-6(9)7-2-4-8(5-3-7)10(11)12;/h2-6H,9H2,1H3;1H/t6-;/m1./s1

Upstream product

• 132873-57-5 (-)-p-nitro-α-methylbenzylamine hydrochloride 

Downstream Products

• 824937-62-4 N-[(2R)-3-phenyl-1-pivaloyloxy-2-propyl]-N'-[(R)-α-methyl-4-aminobenzyl]thiourea 
• 1569819-30-2 (R)-4-(1-((3,3-diphenylallyl)nitro)ethyl)aniline 
• 255060-77-6 (S)-[1-(4-aminophenyl)ethyl]carbamic acid tert-butyl ester 
• 177947-88-5 (S)-tert-butyl 1-(4-nitrophenyl)ethylcarbamate 
• 824937-61-3 N-[(2R)-3-phenyl-1-pivaloyloxy-2-propyl]-N'-[(R)-α-methyl-4-nitrobenzyl]thiourea 
• 694529-17-4 N-(4-t-butylbenzyl)-N'-[(1R)-1-(4-aminophenyl)ethyl]thiourea 
• 910534-76-8 (R)-[1-(4-methanesulfonylaminophenyl)ethyl]carbamic acid t-butyl ester 
• 694529-76-5 (S)-4-methanesulfonamido-α-methylbenzylamine 
• 694529-72-1 [1-(4-acetylamino-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 262368-44-5 (R)-[1-(4-aminophenyl)ethyl]carbamic acid tert-butyl ester 
• 177948-74-2 (R)-N-[4-(1-aminoethyl)phenyl]acetamide 

Relevant articles and documents

Synthesis and pKa determination of new enantiopure dimethyl-substituted acridino-crown ethers containing a carboxyl group: Useful candidates for enantiomeric recognition studies

New enantiopure dimethyl-substituted acridino-18-crown-6 and acridino-21-crown-7 ethers containing a carboxyl group at position 9 of the acridine ring [(S,S)-8, (S,S)-9, (R,R)-10] were synthesized. The pKa values of the new crown ethers [(S,S)-8, (S,S)-9, (R,R)-10] and of an earlier reported macrocycle [(R,R)-2] were determined by UV-pH titrations. Crown ether (S,S)-8 was attached to silica gel by covalent bonds and the enantiomeric separation ability of the newly prepared chiral stationary phase [(S,S)-CSP-12] was studied by high-performance liquid chromatography (HPLC). Homochiral preference was observed and the best separation was achieved for the enantiomers of 1-NEA. Ligands (S,S)-9 and (R,R)-10 are precursors of enantioselective sensor and selector molecules for the enantiomers of protonated primary amines, amino acids, and their derivatives.

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

Salts of the γ-lactone of (-)-threo-hydroxycitric acid with R(+)-α-methyl-p-nitrobenzylamine

Racemic organic carboxylic acids are efficiently resolved into their enantiomers with antipodes of α-methyl-p-nitrobenzylamine.