57234-28-3

Basic information

• Product Name: 1-Methoxy-3-(methoxymethoxy)benzene
• Synonyms: Benzene, 1-methoxy-3-(methoxymethoxy)-
• CAS NO: 57234-28-3
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.192
• Mol File: 57234-28-3.mol

Chemical Properties

• Boiling Point: 247.533 °C at 760 mmHg
• Flash Point: 80.994 °C
• Density: 1.049 g/cm³
• CAS DataBase Reference: 1-Methoxy-3-(methoxymethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methoxy-3-(methoxymethoxy)benzene(57234-28-3)
• EPA Substance Registry System: 1-Methoxy-3-(methoxymethoxy)benzene(57234-28-3)

Safety Data

• Hazardous Substances Data: 57234-28-3(Hazardous Substances Data)

Usage

Uses

Used in Perfumery and Fragrance Industry:
1-Methoxy-3-(methoxymethoxy)benzene is used as a fragrance ingredient for its sweet, aromatic scent, enhancing the olfactory profiles of perfumes and other fragranced products.
Used in Flavoring Industry:
1-Methoxy-3-(methoxymethoxy)benzene serves as a flavoring agent, leveraging its aromatic properties to add depth and complexity to food and beverage products.
Used in Pharmaceutical Industry:
1-Methoxy-3-(methoxymethoxy)benzene is utilized as a precursor in the synthesis of pharmaceutical compounds, contributing to the development of new medications due to its chemical reactivity and structural properties.
Used in Chemical Synthesis:
As a versatile solvent, 1-Methoxy-3-(methoxymethoxy)benzene is employed in various chemical processes, facilitating reactions in industrial applications and aiding in the production of a range of organic compounds.

Upstream product

• 150-19-6 O-methylresorcine 
• 107-30-2 chloromethyl methyl ether 
• 109-87-5 Dimethoxymethane 
• 108-95-2 phenol 
• 13057-17-5 bromethyl methyl ether 
• 154045-69-9 1,2-dimethoxy-3-(methoxymethoxy)benzene 

Downstream Products

• 54246-33-2 (+/-)-2-methyl-2-(4-methyl-3-pentenyl)-5-methoxy-2H-benzopyran 
• 849915-13-5 2-allyl-1-methoxy-3-methoxymethoxybenzene 
• 73220-19-6 6-methoxy-2-(methoxymethoxy)benzaldehyde 
• 336185-10-5 2-tert-butyl-4-methoxybenzaldehyde 
• 372159-47-2 tert-butyl (4S)-4-[hydroxy(2-methoxy-6-(methoxymethoxy)phenyl)methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 81245-38-7 1-iodo-4-methoxy-2-(methoxymethoxy)-benzene 
• 616206-01-0 2-((S)-3-Isopropyl-1-methyl-cyclopent-2-enyl)-1-(2-methoxy-6-methoxymethoxy-phenyl)-ethanone 
• 19399-68-9 1,3-di(p-tolyl)benzene 
• 913622-56-7 1-(2-methoxy-6-(methoxymethoxy)phenyl)propan-2-yl 5-chloro-2,4-dihydroxybenzoate 
• 169212-88-8 butyl-hydroxy-anisole 
• 169212-89-9 2-butyl-1-methoxy-3-(methoxymethoxy)benzene 
• 166409-12-7 2-butyl-3-methoxycyclohexa-2,5-diene-1,4-dione 
• 180912-54-3 2-Cyclohexylmethyl-3-methoxy-phenol 
• 180912-58-7 2-Butyl-5,6-dichloro-3-methoxy-[1,4]benzoquinone 

Relevant articles and documents

Regioselectivity Influences in Platinum-Catalyzed Intramolecular Alkyne O-H and N-H Additions

The steric and electronic drivers of regioselectivity in platinum-catalyzed intramolecular hydroalkoxylation are elucidated. A branch point is found that divides the process between 5-exo and 6-endo selective processes, and enol ethers can be accessed in good yields for both oxygen heterocycles. The main influence arises from an electronic effect, where the alkyne substituent induces a polarization of the alkyne that leads to preferential heteroatom attack at the more electron-deficient carbon. The electronic effects are studied in other contexts, including hydroacyloxylation and hydroamination, and similar trends in directionality are predominant although not uniformly observed.

Synthesis of axially chiral compounds using diastereomeric resolution of racemic-boronic acids

The present invention refers to a portion of the preferred embodiment tax [mik [mik] - biphenyl boronic acid compounds that prevent an axial chirality stereochemical isomerism quality pipe acid; axial chiral biphenyl boronic acid intermediates in synthesizing method number bath using a novel method and axial chiral compound are disclosed. (by machine translation)

Synthesis of axially chiral compounds using diastereomeric resolution of racemic-boronic acids

The present invention refers to a portion of the preferred embodiment tax [mik[mik] - biphenyl boronic acid compounds that prevent an axial chirality stereochemical isomerism quality pipe acid; axial chiral biphenyl boronic acid intermediates in synthesizing method number bath using a novel method and axial chiral compound are disclosed. (by machine translation)

Synthesis of Optically Pure 3,3′-Disubstituted-1,1′-Bi-6-Methoxy-2-Phenol (BIPhOL) Derivatives via Diastereomeric Resolution

A new protocol for the enantioselective synthesis of 3,3′-disubstituted-1,1′-bi-6-methoxy-2-phenol (BIPhOL) derivatives is described. Diastereomeric resolution of racemic BIPhOL boronic acid using a boronic acid moiety as a resolving group generated two diastereomers and subsequent Suzuki-Miyaura coupling reaction of the resulting diastereomers with aryl halides provided BIPhOL derivatives without any loss of enantioselectivity. In addition, the absolute stereochemistry of chiral BIPhOL was determined by comparison of the optical rotation with the reported value.

NOVEL COMPOUNDS

The invention provides compounds of formula (I): Said compounds being modulators of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being modulators of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

Palladium-catalyzed asymmetric synthesis of silicon-stereogenic dibenzosiloles via enantioselective C-H bond functionalization

A Pd-catalyzed asymmetric synthesis of Si-stereogenic dibenzosiloles is developed through enantioselective C-H bond functionalization of prochiral 2-(arylsilyl)aryl triflates. High chemo- and enantioselectivities are achieved by employing a Josiphos-type ligand under mild conditions.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

NOVEL BENZOXATHIIN DERIVATIVE

Disclosed is a compound represented by the formula (I) below and a pharmaceutically acceptable salt thereof. This compound is useful for treatment of obesity, diabetes and the like. [In the formula (I), Ar represents a benzene ring or the like; X1 represents a nitrogen atom, a sulfur atom or the like; R1 represents an aryl group or the like; X2 represents a group represented by the following formula (II): (wherein R4 and R5 respectively represent a lower alkyl group or the like, and m represents a number of 2-4) or the like; one of X and Y represents an oxygen atom and the other represents a sulfanyl group or the like; and X3-X6 respectively represent -CH-, a nitrogen atom or the like.