5725-96-2

Usage

Uses

Used in Industrial Processes:
N,N-Dimethylhydroxylamine is utilized as a reducing agent in various industrial applications, facilitating chemical reactions by donating electrons to other substances.
Used in Water Treatment Chemicals:
It serves as a stabilizer in water treatment processes, helping to maintain the effectiveness and longevity of the chemicals used in these treatments.
Used in Pharmaceutical Production:
N,N-Dimethylhydroxylamine is employed in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Polymer Production:
N,N-Dimethylhydroxylamine is also used in the production of polymers, playing a role in the creation of different types of plastics and other polymer-based materials.
Used in Pesticide Production:
N,N-Dimethylhydroxylamine contributes to the manufacturing of pesticides, aiding in the development of effective agricultural chemicals to protect crops from pests and diseases.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 60-29-7 diethyl ether 
• 625-58-1 ethyl nitrate 
• 628-96-6 1,2-ethyl dinitrate 
• 78-11-5 Pentaerythritol tetranitrate 
• 55-63-0 glycerin trinitrate 
• 75-16-1 methylmagnesium bromide 
• 42142-07-4 dimethyl-(1-phenyl-ethyl)-amine oxide 
• 860701-93-5 dimethyl-(1-methyl-1-phenyl-ethyl)-amine oxide 
• 75-52-5 nitromethane 
• 98-94-2 N,N-dimethyl-cyclohexanamine 
• 20762-86-1 N,N-dimethylbutylamine N-oxide 
• 1201-56-5 (+/-)-N-methylephedrine 
• 124-40-3 dimethyl amine 

Downstream Products

• 5669-36-3 O-butyl-N,N-dimethyl-hydroxylamine 
• 3307-54-8 5.5-Dimethyl-1.1-diphenyl-dihydro-1.2.4.5-boradioxazol 
• 42152-40-9 2-methyl-5-decylisoxazolidine 
• 13948-04-4 N,N-Dimethyl-2-dodecylamin 
• 6039-61-8 N-Aethoxycarbonyloxy-dimethyl-amin 
• 99337-24-3 C₈H₁₁NO₂S 
• 99337-23-2 C₃H₉NO₂S 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 85437-82-7 ((bis(dimethylamino)phosphinyl)oxy)dimethylamine 
• 85437-83-8 C₆H₁₆NO₄P 
• 240493-55-4 C₂₈H₃₃N₂O₄P 
• 124-40-3 dimethyl amine 

Relevant academic research and scientific papers

Method for coproducing vasoxine hydrochloride and N,O-dimethylhydroxylamine hydrochloride

The invention relates to the technical field of compound synthesis methods, particularly a method for coproducing vasoxine hydrochloride and N,O-dimethylhydroxylamine hydrochloride. The method comprises the following steps: carrying out methylation reaction on hydroxylamine salt under alkaline conditions by using a methylating agent to obtain a reaction solution containing vasoxine and N,O-dimethylhydroxylamine, rectifying to separate a vasoxine bottom solution and an N,O-dimethylhydroxylamine crude distillate, respectively adding hydrochloric acid for salification, concentrating and crystallizing under reduced pressure, cooling, carrying out vacuum filtration, recrystallizing with water or methanol, and drying to obtain the vasoxine hydrochloride product and N,O-dimethylhydroxylamine hydrochloride product. The method has the advantages of simple and reliable technique, high product quality, high total yield and low comprehensive cost, and is more friendly to the environment and suitable for industrial production.

MANNICH BASE N-OXIDE DRUGS

The invention relates to Mannich base N-oxides of drugs containing acidic N- H groups. Pharmaceutical compositions comprising therapeutically effective amount of Mannich base N-oxides, or a pharmaceutically acceptable salt or prodrug thereof, are disclosed. Further, the invention relates to methods of using the compounds, alone or in combination with one or more other active agents or treatments, are disclosed.

METHODS FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-HYDROXYCINNAMIC ACID

Three different reaction steps were combined to provide methods for preparing p-hydroxystyrene and p-hydroxycinnamic acid monomers from tyrosine. The three steps include reductive alkylation of tyrosine, followed by oxidation to the N-oxide, and thermal Cope elimination. During Cope elimination, either p-hydroxycinnamic acid or p-hydroxystyrene was produced depending on the absence or presence of base, respectively. Additionally, p-acetoxystyrene may be prepared by reacting the prepared p-hydroxystyrene either directly or after isolation with an acetylating agent.

Tamoxifen stimulates calcium entry into human platelets

The anti-estrogenic drug tamoxifen, which is used therapeutically for treatment and prevention of breast cancer, can lead to the development of thrombosis. We found that tamoxifen rapidly increased intracellular free calcium [Ca]i in human platelets from

A Short and Efficient Synthesis of (S)-4-Methylene Proline Benzyl Ester from (S)-Pyroglutamic Acid

(S)-4-methylene proline benzyl ester 2 was synthesized from benzyl N-tert-butoxycarbonyl pyroglutamate through a Mannich and a Cope elimination reactions.

Pyrimidine derivatives

A pyrimidine derivative represented by the formula STR1 wherein the variables are defined below in the specification, and their production and herbicidal activities are described.

Secondary α hydrogen-deuterium kinetic isotope effects in the syn-elimination reaction of 2-phenylethyldimethylamine oxide

The secondary α-deuterium kinetic isotope effect has been measured for the thermal reaction of 2-phenylethyldimethylamine oxide in 90 mol percent DMSO-H2O at 60.0 deg C.A large secondary α-deuterium isotope effect of 1.158 per α-D was found, which indicates significant C-N bond rupture and very little double bond formation at the transition state for this concerted syn-elimination process.The observed large normal value for (kH/kD)α is discussed in terms of the use of secondary α-D isotope effects for the determination of stereochemistry for a concerted elimination process.Various isotope effects found for the syn elimination of the above amine oxide and those for the anti elimination of 2-arylethyltrimethylammonium salts with ethoxide are considered with respect to the relative transition state structures for syn- and anti-elimination reactions.

Process of preparing hydroxyarylaldehydes

An improvement in the process for preparing hydroxyarylaldehydes is disclosed where a phenolic compound is reacted with formaldehyde, in the presence of a catalyst such as a titanium or zirconium containing catalyst, optionally in the presence of a catalyst promoter, wherein the improvement is the addition of a yield effective amount of a modifier having the formula: STR1 where R1 is selected from the group consisting of: an alkyl group having from 1 to 12 carbon atoms, a cycloalkyl group that can have 5 and 6 carbon atoms, and an H, and where R2 is selected from the group consisting of: an alkyl group having from 1 to 12 carbon atoms, and a cyclo alkyl group that can have 5 to 6 carbon atoms; and where R1 and R2 can together form a cyclic group that can have 5 and 6 carbon atoms.

EVOLUTION THERMIQUE DE N-OXYDES DE DIMETHYLAMINO-5 ALCANOLS-1 SUBSTITUES EN 5. COMPETITION ENTRE REARRANGEMENTS DE COPE ET DE MEISENHEIMER

The effect of the substituent R in the 5 position was studied in the decomposition of 1,5-aminoalcohol N-oxides: Meisenheimer rearrangements takes place when R is the vinyl group but is not observed with the phenyl substituent; elimination to alkenol only