57259-73-1

Upstream product

• 4821-94-7 4,5-dimethoxyphthalic anhydride 
• 71-43-2 benzene 
• 22506-58-7 3,4-dihydro-6,7-dimethoxy-1-phenyl-1H-2-benzopyran 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 100-52-7 benzaldehyde 
• 7446-70-0 aluminium trichloride 

Downstream Products

• 60065-43-2 5,6-Dimethoxy-3-phenylisobenzofuran-1(3H)-one 
• 93435-28-0 2-benzyl-4,5-dimethoxy-benzoic acid 
• 101351-07-9 6,7-dimethoxy-4-phenylphtalazin-1(2H)-one 
• 39794-28-0 6,7-dimethoxy-1-phenyl-phthalazine 
• 101272-57-5 1-chloro-6,7-dimethoxy-4-phenyl-phthalazine 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of 4-aryl-6,7- dimethoxyphthalazines as anticonvulsant agents

4-Aryl-6,7-dimethoxyphthalazin-1(2H)-ones and 4-aryl-1,6,7- trimethoxyphthalazines have been synthesized and tested for their ability to prevent audiogenic seizures in DBA/2 mice. The new compounds are structurally related to anticonvulsant 2,3-benzodiaze

Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents

Aryl-fused- and hetaryl-fused-2,4-diazepines of formula XXXVI, benzodiazocines of formula XXX, benzodiazepines of formula II STR1 δ-aminoamides of formula III and aryldimethanamines of formula XXXVII STR2 wherein A is an aryl or hetaryl ring; R1 is hydrogen, alkyl, aryl or hetaryl; R2 is hydrogen, alkyl, substituted alkyl, or aryl; R3 is alkyl, aryl, aralkyl or heteroatom substituted alkyl or aralkyl; R4 is hydrogen or alkyl; R5 is hydrogen, alkyl, aryl or hetaryl; R6 is hydrogen, alkyl, alkoxy, halogen or a fused benzene ring; R9 is hydrogen, alkyl, or substituted alkyl; and R10 is hydrogen, alkyl, or substituted alkyl. The invention further relates to processes for the preparation of, pharmaceutical compositions containing, and methods of treating cardiac arrhythmia with the compounds of formulas XXXVI, XXX, II, III, and XXXVII.

OXIDATION OF 1-ARYL-6,7-DIMETHOXYISOCHROMANS WITH CHROMIUM(VI) OXIDE IN ACETIC ACID: A NEW SYNTHETIC PATHWAY TO 2-AROYL-4,5-DIMETHOXYBENZALDEHYDES AND 2-ACETYL-4,5-DIMETHOXYBENZOPHENONES

The oxidation of 1-aryl-6,7-dimethoxyisochromans with chromium(VI) oxide in acetic acid does not give the expected 2-aroylphenylacetic acids, but instead leads to a mixture consisting chiefly of 2-aroyl-4,5-dimethoxybenzaldehydes and of the corresponding