57279-72-8Relevant academic research and scientific papers
DISUBSTITUTED ALKYNE DERIVATIVES
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Page/Page column 141, (2020/07/14)
The present invention relates to disubstituted alkyne derivatives. These compounds are useful for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases.
Direct Tryptophols Synthesis from 2-Vinylanilines and Alkynes via C - C Triple Bond Cleavage and Dioxygen Activation
Shen, Tao,Zhang, Yiqun,Liang, Yu-Feng,Jiao, Ning
supporting information, p. 13147 - 13150 (2016/10/24)
An unexpected metal-free C - C triple bond cleavage, dioxygen activation, and reassembly into tryptophol derivatives has been developed. This chemistry provides a novel, simple, and efficient approach to highly valuable tryptophol derivatives from simple substrates under mild conditions. The mechanistic studies may promote the discovery of new methodologies through C-C bond cleavage and dioxygen activation.
Efficient, rapid, and regioselective bromination of phenols and anilines with N-bromosaccharin using tungstophosphoric acid as a heterogeneous recyclable catalyst
Alinezhad, Heshmatollah,Tavakkoli, Sahar Mohseni,Salehian, Fatemeh
experimental part, p. 3226 - 3232 (2010/12/24)
A simple, efficient, and rapid method for high-yielding regioselective mono bromination of phenols and anilines has been achieved by treatment with N-bromasaccharin in the presence of a catalytic amount of tungstophosphoric acid. Copyright Taylor & Francis Group, LLC.
POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
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Page 62; 64-65, (2010/02/08)
The invention provides compounds of Formula (I). These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in wh
