57296-03-4

Basic information

• Product Name: DI(N-SUCCINIMIDYL) OXALATE
• Synonyms: DI(N-SUCCINIMIDYL) OXALATE;DISUCCINIMIDYL OXALATE;DSO;N,N'-DISUCCINIMIDO OXALATE;oxalic acid bis(N-hydroxysuccinimide)*ester;n,n'-disuccinimidyl oxalate;Bis-(N-succinimidyl)-oxalate;N,Nμ-Disuccinimidyl oxalate, Di(N-succinimidyl) oxalate, DSO
• CAS NO: 57296-03-4
• Molecular Formula: C₁₀H₈N₂O₈
• Molecular Weight: 284.18
• Mol File: 57296-03-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 239 °C (dec.)(lit.)
• Boiling Point: 427.9°Cat760mmHg
• Flash Point: 212.6°C
• Appearance: /
• Density: 1.72g/cm³
• Vapor Pressure: 1.58E-07mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 4562450
• CAS DataBase Reference: DI(N-SUCCINIMIDYL) OXALATE(CAS DataBase Reference)
• NIST Chemistry Reference: DI(N-SUCCINIMIDYL) OXALATE(57296-03-4)
• EPA Substance Registry System: DI(N-SUCCINIMIDYL) OXALATE(57296-03-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 57296-03-4(Hazardous Substances Data)

Usage

General Description

DI(N-Succinimidyl) Oxalate is a chemical compound used in bioconjugation reactions to crosslink amine-containing molecules. It reacts with primary amines to form stable amide bonds, making it a commonly used reagent in the development of protein-protein, protein-nucleic acid, and protein-small molecule conjugates. The resulting amide bonds are stable under physiological conditions, making the compound useful for a wide range of applications including drug delivery, diagnostics, and biomaterials. Additionally, DI(N-Succinimidyl) Oxalate is known for its high reactivity and selectivity, making it a valuable tool in the field of chemical biology and bioconjugation chemistry.

InChI:InChI=1/C10H8N2O8/c13-5-1-2-6(14)11(5)19-9(17)10(18)20-12-7(15)3-4-8(12)16/h1-4H2

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 3401-36-3 (N-benzyloxycarbonyl)-L-alanine N-hydroxysuccinimide ester 
• 106086-12-8 N-Oxysuccinimide N'-tert-butyloxycarbonyl-2-phenylthiazolidine-4-carboxylate 
• 3397-32-8 N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester 
• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 

Relevant articles and documents

Preparation method of lithium difluorobisoxalate phosphate solution

The invention provides a preparation method of a lithium difluorobisoxalate phosphate solution, and the method comprises the following steps: 1) reacting N-hydroxysuccinimide and oxalyl chloride in anon-aqueous solvent to obtain a di (N-succinimido) oxalic acid solution; and 2) adding lithium hexafluorophosphate into the di (N-succinimido) oxalic acid solution, and reacting to obtain the lithiumdifluorobisoxalate phosphate solution. According to the preparation method, the obtained solution can be directly used for lithium salt electrolyte materials of lithium ion batteries without further purification, and the method has the advantages of cheap and easily available reaction raw materials, simple operation, environmental friendliness of byproducts, and suitability for industrial production.

Chemiluminescence

Novel O-oxalylhydroxyl-amine compositions of matter and reactions and to the direct generation of light from chemical energy employing such compositions. By "light" as referred to herein is meant electromagnetic radiation at wavelengths falling between about 350 mμ and 800 mμ. Disclosed compounds include diphthalimide oxalate, disuccinimido oxalate, and dimaleimido oxalate.